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The synthesis features a <jats:italic>syn<\/jats:italic>\u2010selective vinylogous Kobayashi aldol reaction, recently developed by us, and a ring\u2010closing intramolecular Heck reaction as the pivotal transformations. Comparison of the NMR spectra of the authentic and synthetic material revealed that the proposed configuration had to be revised. A combination of molecular modeling and NOE experiments was used to propose the revised configuration, which was confirmed by a new synthesis.<\/jats:p>","DOI":"10.1002\/anie.201309386","type":"journal-article","created":{"date-parts":[[2014,1,13]],"date-time":"2014-01-13T11:16:22Z","timestamp":1389611782000},"page":"1795-1798","source":"Crossref","is-referenced-by-count":44,"title":["Structure Elucidation and Total Synthesis of Kulkenon"],"prefix":"10.1002","volume":"53","author":[{"given":"Gerrit","family":"Symkenberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Kalesse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,1,13]]},"reference":[{"key":"e_1_2_2_1_2","unstructured":"\u00a0"},{"key":"e_1_2_2_2_2","first-page":"109","volume-title":"Scientific Annual Report of the GBF: Biological active secondary metabolites 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