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Described herein is a simple reaction system consisting of the sulfur dioxide surrogate DABSO, triethylamine, and a palladium(0) catalyst for effective convertion of a broad range of aryl and heteroaryl halides into the corresponding ammonium sulfinates. Key features of this gas\u2010 and reductant\u2010free reaction include the low loadings of palladium (1\u2005mol\u2009%) and ligand (1.5\u2005mol\u2009%) which can be employed, and the use of isopropyl alcohol as both a solvent and formal reductant. The ammonium sulfinate products are converted in situ into a variety of sulfonyl\u2010containing functional groups, including sulfones, sulfonyl chlorides, and sulfonamides.<\/jats:p>","DOI":"10.1002\/anie.201404527","type":"journal-article","created":{"date-parts":[[2014,7,27]],"date-time":"2014-07-27T22:43:03Z","timestamp":1406500983000},"page":"10204-10208","source":"Crossref","is-referenced-by-count":203,"title":["Palladium\u2010Catalyzed Synthesis of Ammonium Sulfinates from Aryl Halides and a Sulfur Dioxide Surrogate: A Gas\u2010 and Reductant\u2010Free Process"],"prefix":"10.1002","volume":"53","author":[{"given":"Edward J.","family":"Emmett","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry R.","family":"Hayter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C.","family":"Willis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,7,27]]},"reference":[{"key":"e_1_2_2_1_2","unstructured":"For example:"},{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2004.12.017"},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm100398z"},{"key":"e_1_2_2_4_2","first-page":"72","volume":"11","author":"Smith D. 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