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This finding enables the convergent synthesis of proteins from readily synthesizable peptide <jats:italic>o<\/jats:italic>\u2010aminoanilides as a new type of crypto\u2010thioesters. The practicality of this approach is shown by the synthesis of histone H2B from five peptide segments. Purification or solubilization tags, which are sometimes needed to improve the efficiency of protein chemical synthesis, can be incorporated into the <jats:italic>o<\/jats:italic>\u2010aminoanilide moiety, as demonstrated in the preparation of the cyclic protein lactocyclicin\u2005Q.<\/jats:p>","DOI":"10.1002\/anie.201408078","type":"journal-article","created":{"date-parts":[[2014,12,7]],"date-time":"2014-12-07T15:34:20Z","timestamp":1417966460000},"page":"2194-2198","source":"Crossref","is-referenced-by-count":174,"title":["Peptide <i>o<\/i>\u2010Aminoanilides as Crypto\u2010Thioesters for Protein Chemical 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