{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T22:14:26Z","timestamp":1785190466976,"version":"3.55.0"},"reference-count":61,"publisher":"Wiley","issue":"34","license":[{"start":{"date-parts":[[2016,7,13]],"date-time":"2016-07-13T00:00:00Z","timestamp":1468368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL116571"],"award-info":[{"award-number":["R01HL116571"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2016,8,16]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hydrogen sulfide (H<jats:sub>2<\/jats:sub>S) and hydrogen polysulfides (H<jats:sub>2<\/jats:sub>S<jats:sub><jats:italic>n<\/jats:italic><\/jats:sub>, <jats:italic>n<\/jats:italic>&gt;1) are endogenous regulators of many physiological processes. In order to better understand the symbiotic relationship and cellular cross\u2010talk between H<jats:sub>2<\/jats:sub>S and H<jats:sub>2<\/jats:sub>S<jats:sub><jats:italic>n<\/jats:italic><\/jats:sub>, it is highly desirable to develop single fluorescent probes which enable dual\u2010channel discrimination between H<jats:sub>2<\/jats:sub>S and H<jats:sub>2<\/jats:sub>S<jats:sub><jats:italic>n<\/jats:italic><\/jats:sub>. Herein, we report the rational design, synthesis, and evaluation of the first dual\u2010detection fluorescent probe <jats:bold>DDP\u20101<\/jats:bold> that can visualize H<jats:sub>2<\/jats:sub>S and H<jats:sub>2<\/jats:sub>S<jats:sub><jats:italic>n<\/jats:italic><\/jats:sub> with different fluorescence signals. The probe showed high selectivity and sensitivity to H<jats:sub>2<\/jats:sub>S and H<jats:sub>2<\/jats:sub>S<jats:sub>n<\/jats:sub> in aqueous media and in cells.<\/jats:p>","DOI":"10.1002\/anie.201604892","type":"journal-article","created":{"date-parts":[[2016,7,13]],"date-time":"2016-07-13T16:54:24Z","timestamp":1468428864000},"page":"9993-9996","source":"Crossref","is-referenced-by-count":285,"title":["A Single Fluorescent Probe to Visualize Hydrogen Sulfide and Hydrogen Polysulfides with Different Fluorescence Signals"],"prefix":"10.1002","volume":"55","author":[{"given":"Wei","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Chemistry Washington State University  Pullman WA 99164 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armando","family":"Pacheco","sequence":"additional","affiliation":[{"name":"Department of Chemistry Washington State University  Pullman WA 99164 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