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The photo\u2010tether strategy presented here provides a robust and versatile tool for the light\u2010activation of longer functional oligonucleotides, noteworthy without prior knowledge on the structure and the importance of specific nucleotides within a DNA aptamer.<\/jats:p>","DOI":"10.1002\/anie.201610025","type":"journal-article","created":{"date-parts":[[2016,11,29]],"date-time":"2016-11-29T10:14:30Z","timestamp":1480414470000},"page":"359-363","source":"Crossref","is-referenced-by-count":56,"title":["Photo\u2010Tethers for the (Multi\u2010)Cyclic, Conformational Caging of Long Oligonucleotides"],"prefix":"10.1002","volume":"56","author":[{"given":"Patrick","family":"Seyfried","sequence":"first","affiliation":[{"name":"Goethe University Frankfurt Institute for Organic Chemistry and Chemical Biology Buchmann Institute for Molecular Life Sciences  Max-von-Laue-Str. 9 60438 Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Eiden","sequence":"additional","affiliation":[{"name":"Life and Medical Science Institute University of Bonn  Gerhard-Domagk-Str. 1 53121 Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolai","family":"Grebenovsky","sequence":"additional","affiliation":[{"name":"Goethe University Frankfurt Institute for Organic Chemistry and Chemical Biology Buchmann Institute for Molecular Life Sciences  Max-von-Laue-Str. 9 60438 Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fcnter","family":"Mayer","sequence":"additional","affiliation":[{"name":"Life and Medical Science Institute University of Bonn  Gerhard-Domagk-Str. 1 53121 Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3541-4548","authenticated-orcid":false,"given":"Alexander","family":"Heckel","sequence":"additional","affiliation":[{"name":"Goethe University Frankfurt Institute for Organic Chemistry and Chemical Biology Buchmann Institute for Molecular Life Sciences  Max-von-Laue-Str. 9 60438 Frankfurt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,29]]},"reference":[{"key":"e_1_2_2_1_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201202134"},{"key":"e_1_2_2_1_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201202134"},{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr300177k"},{"key":"e_1_2_2_3_1","doi-asserted-by":"crossref","unstructured":"B.\u2005K. 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