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The reaction is general and occurs even for finger\u20053 of the transcription factor Sp1, containing a ZnCys<jats:sub>2<\/jats:sub>His<jats:sub>2<\/jats:sub> coordination sphere. This reaction is the first demonstration of group transfer from a coordination compound to biologically important zinc fingers, and is especially noteworthy for the ZnCys<jats:sub>2<\/jats:sub>His<jats:sub>2<\/jats:sub> transcription factors. The work expands the corpus of organometallic species which can efficiently modify biomolecules through C\u2010atom transfer. The electronic features of the gold compound leading to this unexpected reaction were explored by X\u2010ray absorption spectroscopy.<\/jats:p>","DOI":"10.1002\/anie.201803082","type":"journal-article","created":{"date-parts":[[2018,6,5]],"date-time":"2018-06-05T16:08:37Z","timestamp":1528214917000},"page":"9305-9309","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Gold\u2010Catalyzed C\u2013S Aryl\u2010Group Transfer in Zinc Finger Proteins"],"prefix":"10.1002","volume":"57","author":[{"given":"Raphael E. F.","family":"de\u2005Paiva","sequence":"first","affiliation":[{"name":"Department of Chemistry Virginia Commonwealth University  1001 W. Main Street Richmond VA 23284-2006 USA"},{"name":"Institute of Chemistry University of Campinas\u2014UNICAMP  P.O. 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