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Multipronged efforts may resolve these complexities. To achieve interesting nanostructure\u2010driven optical properties, a dual\u2010biomimetic system contained within a single nanoagent was engineered to recapitulate chlorosomes, efficient light\u2010harvesting organelles that have unique dye assemblies and tunable photonic properties. A series of chlorin dyes was synthesized, and these hydrophobic assemblies were stabilized inside a high\u2010density lipoprotein, a second biomimetic that enabled in vivo utility. This system resulted in tunable tumor imaging of intact (photoacoustic) and disrupted (activatable fluorescence) nanostructures. 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