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The addition of B\n                    <jats:sub>2<\/jats:sub>\n                    pin\n                    <jats:sub>2<\/jats:sub>\n                    to a carbonyl compound generates \u03b1\u2010oxyl\u2010substituted alkyl boron species. Organolithium and Grignard reagents are then applied as C\u2005nucleophiles for the 1,2\u2010metalate rearrangement process. The organolithium reagents can also be generated by C\u2212H lithiation or halogen\/lithium exchange. The use of chiral ligands led to the generation of chiral alkyl boronic esters in enantioenriched form, demonstrating that the enantioselectivity of this transformation is catalyst\u2010controlled.\n                  <\/jats:p>","DOI":"10.1002\/anie.201804684","type":"journal-article","created":{"date-parts":[[2018,6,11]],"date-time":"2018-06-11T12:27:36Z","timestamp":1528720056000},"page":"10318-10322","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Synthesis of Secondary and Tertiary Alkyl Boronic Esters by\n                    <i>gem<\/i>\n                    \u2010Carboborylation: Carbonyl Compounds as Bis(electrophile) Equivalents"],"prefix":"10.1002","volume":"57","author":[{"given":"Dunfa","family":"Shi","sequence":"first","affiliation":[{"name":"State Key Laboratory for Oxo Synthesis and Selective Oxidation Suzhou Research Institute of LICP Lanzhou Institute of Chemical Physics (LICP) Chinese Academy of Sciences  Lanzhou 730000 P. 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