{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:27:44Z","timestamp":1786976864983,"version":"build-2736575974"},"reference-count":58,"publisher":"Wiley","issue":"32","license":[{"start":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T00:00:00Z","timestamp":1559174400000},"content-version":"am","delay-in-days":324,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#am"},{"start":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T00:00:00Z","timestamp":1531180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000086","name":"Directorate for Mathematical and Physical Sciences","doi-asserted-by":"publisher","award":["CHE-1664632"],"award-info":[{"award-number":["CHE-1664632"]}],"id":[{"id":"10.13039\/100000086","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2018,8,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Reported is a general procedure to synthesize tetrasubstituted enones, which are borylated in the \u03b2\u2010position, using a copper\u2010catalyzed four\u2010component coupling reaction of simple chemical feedstocks: internal alkynes, alkyl halides, bis(pinacolato)diboron (B\n                    <jats:sub>2<\/jats:sub>\n                    pin\n                    <jats:sub>2<\/jats:sub>\n                    ), and CO. A broad scope of highly functionalized \u03b2\u2010borylated enones, a largely unknown class of organic compounds, can be accessed efficiently using this method. The synthesis of all\u2010carbon tetrasubstituted enones was realized by employing the \u03b2\u2010borylated enone unit, without purification, in a Suzuki\u2013Miyaura coupling. The utility of the method was further demonstrated by various transformations, including halogenation, oxidation, and protodeboration, of the corresponding reduced oxaborole species to provide densely substituted allylic alcohol and ketone products.\n                  <\/jats:p>","DOI":"10.1002\/anie.201804883","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T09:55:22Z","timestamp":1527674122000},"page":"10328-10332","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":79,"title":["Copper\u2010Catalyzed Borocarbonylative Coupling of Internal Alkynes with Unactivated Alkyl Halides: Modular Synthesis of Tetrasubstituted \u03b2\u2010Borylenones"],"prefix":"10.1002","volume":"57","author":[{"given":"Li\u2010Jie","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Chemistry University of Illinois at Chicago  845 W. Taylor St. Chicago IL 60607 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6923-5164","authenticated-orcid":false,"given":"Neal P.","family":"Mankad","sequence":"additional","affiliation":[{"name":"Department of Chemistry University of Illinois at Chicago  845 W. 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