{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T08:30:04Z","timestamp":1777710604730,"version":"3.51.4"},"reference-count":94,"publisher":"Wiley","issue":"40","license":[{"start":{"date-parts":[[2018,9,4]],"date-time":"2018-09-04T00:00:00Z","timestamp":1536019200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2017R1A2B4010888"],"award-info":[{"award-number":["NRF-2017R1A2B4010888"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2014-011165"],"award-info":[{"award-number":["NRF-2014-011165"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2012M3A7B4049653"],"award-info":[{"award-number":["NRF-2012M3A7B4049653"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Intermolecular asymmetric gold catalysis involving alkyne activation presents a significant challenge due to its distinct mechanistic mode from other metals. Herein, we report a highly enantioselective synthesis of \u03b1,\u03b2\u2010unsaturated \u03b4\u2010lactones from [4+2] annulation of propiolates and alkenes in upto 95\u2009% <jats:italic>ee<\/jats:italic>. Notably, for the desired chiral recognition, the choice of 1,1,2,2\u2010tetrachloroethane as solvent was found to be crucial. Furthermore, an anionic surfactant (sodium dodecyl sulfate) improved the product selectivity in the divergence of the cyclopropyl gold carbene intermediate.<\/jats:p>","DOI":"10.1002\/anie.201807514","type":"journal-article","created":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T15:44:05Z","timestamp":1534952645000},"page":"13130-13134","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Asymmetric Synthesis of Dihydropyranones via Gold(I)\u2010Catalyzed Intermolecular [4+2] Annulation of Propiolates and Alkenes"],"prefix":"10.1002","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5981-0380","authenticated-orcid":false,"given":"Hanbyul","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Chemistry, Research Institute for Natural Sciences and Center for New Directions in Organic Synthesis (CNOS) Hanyang University  222 Wangsimni-ro, Seongdong-gu Seoul 04763 Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su Yeon","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Research Institute for Natural Sciences and Center for New Directions in Organic Synthesis (CNOS) Hanyang University  222 Wangsimni-ro, Seongdong-gu Seoul 04763 Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1702-8918","authenticated-orcid":false,"given":"Seunghoon","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Research Institute for Natural Sciences and Center for New Directions in Organic Synthesis (CNOS) Hanyang University  222 Wangsimni-ro, Seongdong-gu Seoul 04763 Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,4]]},"reference":[{"key":"e_1_2_2_1_1","unstructured":"\u00a0"},{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/np50076a017"},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm00382a001"},{"key":"e_1_2_2_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1565(199907\/08)10:4<161::AID-PCA453>3.0.CO;2-2"},{"key":"e_1_2_2_5_1","first-page":"1","volume-title":"Topics in Heterocyclic Chemistry","author":"Mascare\u00f1as J. 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