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The method allows access to a)\u2005<jats:italic>P<\/jats:italic>\u2010chiral biaryl phosphine oxides, b)\u2005atropo\u2010enantioselective construction of sterically demanding biaryl backbones, and also c)\u2005selective assembly of axial and <jats:italic>P<\/jats:italic>\u2010chiral compounds in excellent yields and diastereo\u2010 and enantioselectivities. Enantiospecific reductions provide monodentate chiral phosphorus(III) compounds having structures and biaryl backbones with proven importance as ligands in asymmetric catalysis.<\/jats:p>","DOI":"10.1002\/anie.201807749","type":"journal-article","created":{"date-parts":[[2018,7,25]],"date-time":"2018-07-25T12:41:03Z","timestamp":1532522463000},"page":"12901-12905","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":356,"title":["Access to <i>P<\/i>\u2010 and Axially Chiral Biaryl Phosphine Oxides by Enantioselective Cp<sup>x<\/sup>Ir<sup>III<\/sup>\u2010Catalyzed C\u2212H Arylations"],"prefix":"10.1002","volume":"57","author":[{"given":"Yun\u2010Suk","family":"Jang","sequence":"first","affiliation":[{"name":"Laboratory of Asymmetric Catalysis and Synthesis EPFL SB ISIC LCSA, BCH 4305, CH-  1015 Lausanne 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