{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T12:31:53Z","timestamp":1790512313901,"version":"4.1.0"},"reference-count":68,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,1,20]],"date-time":"2020-01-20T00:00:00Z","timestamp":1579478400000},"content-version":"am","delay-in-days":347,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#am"},{"start":{"date-parts":[[2019,2,7]],"date-time":"2019-02-07T00:00:00Z","timestamp":1549497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["17H03019"],"award-info":[{"award-number":["17H03019"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["15H05800"],"award-info":[{"award-number":["15H05800"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["18H04646"],"award-info":[{"award-number":["18H04646"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009023","name":"Precursory Research for Embryonic Science and Technology","doi-asserted-by":"publisher","award":["JY290145"],"award-info":[{"award-number":["JY290145"]}],"id":[{"id":"10.13039\/501100009023","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2019,2,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Efficient, phosphine\u2010directed\n                    <jats:italic>ortho<\/jats:italic>\n                    C\u2212H borylation of arylphosphine derivatives was achieved using Ru catalysts for the first time. The reaction is applicable to various tertiary arylphosphine and arylphosphinite derivatives to give (\n                    <jats:italic>o<\/jats:italic>\n                    \u2010borylaryl)phosphorus compounds in high yields. This reaction enables easy access to a variety of functionalized phosphine ligands and ambiphilic phosphine boronate compounds, thus realizing a new late\u2010stage modification of phosphorus compounds.\n                  <\/jats:p>","DOI":"10.1002\/anie.201813278","type":"journal-article","created":{"date-parts":[[2019,1,20]],"date-time":"2019-01-20T21:55:51Z","timestamp":1548021351000},"page":"2850-2853","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":96,"title":["Ruthenium\u2010Catalyzed\n                    <i>ortho<\/i>\n                    C\u2212H Borylation of Arylphosphines"],"prefix":"10.1002","volume":"58","author":[{"given":"Kazuishi","family":"Fukuda","sequence":"first","affiliation":[{"name":"Department of Chemistry School of Science Tokyo Institute of Technology  O-okayama Meguro-ku Tokyo 152-8551 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6323-6588","authenticated-orcid":false,"given":"Nobuharu","family":"Iwasawa","sequence":"additional","affiliation":[{"name":"Department of Chemistry School of Science Tokyo Institute of Technology  O-okayama Meguro-ku Tokyo 152-8551 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4582-2521","authenticated-orcid":false,"given":"Jun","family":"Takaya","sequence":"additional","affiliation":[{"name":"Department of Chemistry School of Science Tokyo Institute of Technology  O-okayama Meguro-ku Tokyo 152-8551 Japan"},{"name":"JST PRESTO, Honcho  Kawaguchi Saitama 332-0012 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,7]]},"reference":[{"key":"e_1_2_2_1_1","unstructured":"\u00a0"},{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3ra42088d"},{"key":"e_1_2_2_3_2","first-page":"317","author":"Valentine D.","year":"2003","journal-title":"Synthesis"},{"key":"e_1_2_2_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2741"},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2017.11.051"},{"key":"e_1_2_2_6_1","unstructured":"\u00a0"},{"key":"e_1_2_2_7_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8CC02821D"},{"key":"e_1_2_2_8_2","doi-asserted-by":"publisher","DOI":"10.1039\/C3CS60418G"},{"key":"e_1_2_2_9_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8CS00201K"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2005.10.003"},{"key":"e_1_2_2_11_1","unstructured":"\u00a0"},{"key":"e_1_2_2_12_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol4012794"},{"key":"e_1_2_2_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201404151"},{"key":"e_1_2_2_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.5b01896"},{"key":"e_1_2_2_15_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.7b00167"},{"key":"e_1_2_2_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201807749"},{"key":"e_1_2_2_16_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201807749"},{"key":"e_1_2_2_17_1","unstructured":"For examples of C\u2212H functionalization using the phosphorus moiety as a removable directing group see:"},{"key":"e_1_2_2_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200390037"},{"key":"e_1_2_2_18_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200390005"},{"key":"e_1_2_2_19_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo030157k"},{"key":"e_1_2_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2003.09.151"},{"key":"e_1_2_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2017.03.055"},{"key":"e_1_2_2_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201402868"},{"key":"e_1_2_2_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201402868"},{"key":"e_1_2_2_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201703354"},{"key":"e_1_2_2_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201703354"},{"key":"e_1_2_2_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b00305"},{"key":"e_1_2_2_25_1","unstructured":"\u00a0"},{"key":"e_1_2_2_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201307115"},{"key":"e_1_2_2_26_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201307115"},{"key":"e_1_2_2_27_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b03394"},{"key":"e_1_2_2_28_1","unstructured":"\u00a0"},{"key":"e_1_2_2_29_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr900206p"},{"key":"e_1_2_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2017.11.005"},{"key":"e_1_2_2_31_1","unstructured":"CAUTION! This reaction should be conducted behind an explosion-proof wall. It is performed in a sealed glass tube at 100\u2009\u00b0C which is over the boiling point of benzene and H2is generated during the reaction."},{"key":"e_1_2_2_32_1","unstructured":"\u00a0"},{"key":"e_1_2_2_33_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol2008457"},{"key":"e_1_2_2_34_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3tc30918e"},{"key":"e_1_2_2_35_2","doi-asserted-by":"publisher","DOI":"10.1039\/c4cc02096k"},{"key":"e_1_2_2_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/cctc.201500110"},{"key":"e_1_2_2_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201604943"},{"key":"e_1_2_2_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2018.05.038"},{"key":"e_1_2_2_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja405925w"},{"key":"e_1_2_2_40_1","unstructured":"The same site-selectivity to give9was observed in the Ir-catalyzed reaction (Ref [6]). However the selective formation of the double borylation product was not reported with the Ir-catalyst."},{"key":"e_1_2_2_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201107334"},{"key":"e_1_2_2_41_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201107334"},{"key":"e_1_2_2_42_1","unstructured":"One of the possible candidates for the rate-determining step could be the C\u2212B bond-forming reductive elimination. In some Ru-catalyzed sp2C\u2212H bond activation reactions acceleration of C\u2212C bond-forming reductive elimination with electron-withdrawing substituents on the arene was reported. See:"},{"key":"e_1_2_2_43_2","doi-asserted-by":"publisher","DOI":"10.1246\/cl.2001.918"},{"key":"e_1_2_2_44_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201208446"},{"key":"e_1_2_2_44_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201208446"},{"key":"e_1_2_2_45_1","doi-asserted-by":"publisher","DOI":"10.1021\/om200472x"},{"key":"e_1_2_2_46_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja042491j"},{"key":"e_1_2_2_47_1","unstructured":"For selected examples see:"},{"key":"e_1_2_2_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201000520"},{"key":"e_1_2_2_48_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201000520"},{"key":"e_1_2_2_49_2","doi-asserted-by":"publisher","DOI":"10.1002\/9781118839621.ch9"},{"key":"e_1_2_2_50_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b03023"},{"key":"e_1_2_2_51_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8CC03369B"},{"key":"e_1_2_2_52_1","unstructured":"(o-Borylphenyl)phosphine derivatives are usually synthesized from (o-bromophenyl)phosphines by lithiation followed by reaction with boron electrophiles. See:"},{"key":"e_1_2_2_53_2","unstructured":"ref.\u2005[16a];"},{"key":"e_1_2_2_54_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja804492y"},{"key":"e_1_2_2_55_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b00167"},{"key":"e_1_2_2_56_1","unstructured":"Related papers on borylation of tertiary phosphines appeared during the revision process. See:"},{"key":"e_1_2_2_57_2","author":"Wen J.","year":"2019","journal-title":"Angew. Chem. Int. Ed."},{"key":"e_1_2_2_57_3","unstructured":"Angew. Chem. 2019"},{"key":"e_1_2_2_58_2","author":"Wright S.","year":"2019","journal-title":"Angew. Chem. Int. Ed."},{"key":"e_1_2_2_58_3","unstructured":"Angew. 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