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Light\u2010activated quantum dots (QDs) are alternative antimicrobials, with efficient transport, low cost, and therapeutic efficacy, and they can act as antibiotic potentiators, with a mechanism of action orthogonal to small\u2010molecule drugs. Furthermore, light\u2010activation enhances control over the spatiotemporal release and dose of the therapeutic superoxide radicals from QDs. However, the limited deep\u2010tissue penetration of visible light needed for QD activation, and concern over trace heavy metals, have prevented further translation. Herein, we report two indium phosphide (InP) QDs that operate in the near\u2010infrared and deep\u2010red light window, enabling deeper tissue penetration. These heavy\u2010metal\u2010free QDs eliminate MDR pathogenic bacteria, while remaining non\u2010toxic to host human cells. This work provides a pathway for advancing QD nanotherapeutics to combat MDR superbugs.<\/jats:p>","DOI":"10.1002\/anie.201906501","type":"journal-article","created":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T16:33:39Z","timestamp":1560270819000},"page":"11414-11418","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Near\u2010Infrared\u2010Light\u2010Triggered Antimicrobial Indium Phosphide Quantum Dots"],"prefix":"10.1002","volume":"58","author":[{"given":"Max","family":"Levy","sequence":"first","affiliation":[{"name":"Department of Chemical and Biological Engineering, University of Colorado Boulder  Boulder CO USA"},{"name":"Renewable and Sustainable Energy Institute, University of Colorado Boulder  Boulder CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John R.","family":"Bertram","sequence":"additional","affiliation":[{"name":"Renewable and Sustainable Energy Institute, University of Colorado Boulder  Boulder CO USA"},{"name":"Materials Science and Engineering, University of Colorado Boulder  Boulder CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen A.","family":"Eller","sequence":"additional","affiliation":[{"name":"Department of Chemical and Biological Engineering, University of Colorado Boulder  Boulder CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anushree","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Department of Chemical and Biological Engineering, University of Colorado Boulder  Boulder CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7966-2554","authenticated-orcid":false,"given":"Prashant","family":"Nagpal","sequence":"additional","affiliation":[{"name":"Department of Chemical and Biological Engineering, University of Colorado Boulder  Boulder CO USA"},{"name":"Renewable and Sustainable Energy Institute, University of Colorado Boulder  Boulder CO USA"},{"name":"Materials Science and Engineering, University of Colorado Boulder  Boulder CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,4]]},"reference":[{"key":"e_1_2_2_1_1","unstructured":"The Review on Antimicrobial Resistance J. 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