{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:41:00Z","timestamp":1787503260125,"version":"build-2736575974"},"reference-count":70,"publisher":"Wiley","issue":"39","license":[{"start":{"date-parts":[[2019,8,14]],"date-time":"2019-08-14T00:00:00Z","timestamp":1565740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21602114, 21871147"],"award-info":[{"award-number":["21602114, 21871147"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin City","doi-asserted-by":"publisher","award":["16JCYBJC42500"],"award-info":[{"award-number":["16JCYBJC42500"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2019,9,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We have developed a method for the highly diastereo\u2010 and enantioselective construction of 2,3\u2010dihydrobenzofurans bearing tetrasubstituted carbon stereocenters by means of annulation reactions between carbenes and 2\u2010iminyl\u2010 or 2\u2010acyl\u2010substituted phenols through catalysis by readily accessible copper(I)\/bisoxazoline catalysts under mild conditions. These reactions feature a unique mechanism in which the copper catalyst serves a dual function: first it reacts with the diazo compound to generate a metal carbene, and second, upon formation of an oxonium ylide, it acts as a Lewis acid to activate the imine or ketone for diastereo\u2010 and enantioselective cyclization.<\/jats:p>","DOI":"10.1002\/anie.201907943","type":"journal-article","created":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T23:49:57Z","timestamp":1564184997000},"page":"13885-13889","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Copper\u2010Catalyzed Asymmetric Annulation Reactions of Carbenes with 2\u2010Iminyl\u2010 or 2\u2010Acyl\u2010Substituted Phenols: Convenient Access to Enantioenriched 2,3\u2010Dihydrobenzofurans"],"prefix":"10.1002","volume":"58","author":[{"given":"Xin\u2010Shen","family":"Liang","sequence":"first","affiliation":[{"name":"State Key Laboratory and Institute of Elemento-Organic Chemistry College of Chemistry, Nankai University  94 Weijin Road Tianjin 300071 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui\u2010Dong","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory and Institute of Elemento-Organic Chemistry College of Chemistry, Nankai University  94 Weijin Road Tianjin 300071 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5863-0804","authenticated-orcid":false,"given":"Xiao\u2010Chen","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory and Institute of Elemento-Organic Chemistry College of Chemistry, Nankai University  94 Weijin Road Tianjin 300071 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,14]]},"reference":[{"key":"e_1_2_2_1_1","unstructured":"\u00a0"},{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2015.01.021"},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8NP00072G"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.43.247"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(98)00725-0"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1039\/c39820001150"},{"key":"e_1_2_2_7_1","unstructured":"Selected reports:"},{"key":"e_1_2_2_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b03311"},{"key":"e_1_2_2_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201700171"},{"key":"e_1_2_2_10_2","doi-asserted-by":"publisher","DOI":"10.1039\/C7OB00484B"},{"key":"e_1_2_2_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201601186"},{"key":"e_1_2_2_12_1","unstructured":"Selected reports:"},{"key":"e_1_2_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2017.06.015"},{"key":"e_1_2_2_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201501184"},{"key":"e_1_2_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2018.01.039"},{"key":"e_1_2_2_16_1","unstructured":"Selected reports:"},{"key":"e_1_2_2_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol0157858"},{"key":"e_1_2_2_18_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol0267127"},{"key":"e_1_2_2_19_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol060893l"},{"key":"e_1_2_2_20_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja508586t"},{"key":"e_1_2_2_21_1","unstructured":"Selected reports:"},{"key":"e_1_2_2_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201806372"},{"key":"e_1_2_2_22_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201806372"},{"key":"e_1_2_2_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201805831"},{"key":"e_1_2_2_23_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201805831"},{"key":"e_1_2_2_24_1","unstructured":"Reviews:"},{"key":"e_1_2_2_25_2","volume-title":"Modern Catalytic Methods for Organic Synthesis with Diazo Compounds","author":"Doyle M. P.","year":"1998"},{"key":"e_1_2_2_26_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr950022h"},{"key":"e_1_2_2_27_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr00028a010"},{"key":"e_1_2_2_28_1","unstructured":"Selected reports on asymmetric O\u2212H insertion reactions:"},{"key":"e_1_2_2_29_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja0607739"},{"key":"e_1_2_2_30_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja074729k"},{"key":"e_1_2_2_31_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201309820"},{"key":"e_1_2_2_31_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201309820"},{"key":"e_1_2_2_32_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.7b00194"},{"key":"e_1_2_2_33_2","doi-asserted-by":"publisher","DOI":"10.1039\/C7OB01628J"},{"key":"e_1_2_2_34_1","unstructured":"Selected reports on oxonium ylide additions to electrophiles:"},{"key":"e_1_2_2_35_2","doi-asserted-by":"publisher","DOI":"10.1021\/ar300340k"},{"key":"e_1_2_2_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200604389"},{"key":"e_1_2_2_36_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200604389"},{"key":"e_1_2_2_37_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja801755z"},{"key":"e_1_2_2_38_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo101559p"},{"key":"e_1_2_2_39_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200904905"},{"key":"e_1_2_2_39_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200904905"},{"key":"e_1_2_2_40_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5CC01979F"},{"key":"e_1_2_2_41_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b01207"},{"key":"e_1_2_2_42_1","unstructured":"Selected reports on ammonium ylide additions to electrophiles:"},{"key":"e_1_2_2_43_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja201589k"},{"key":"e_1_2_2_44_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3cc36972b"},{"key":"e_1_2_2_45_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201407740"},{"key":"e_1_2_2_45_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201407740"},{"key":"e_1_2_2_46_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b01744"},{"key":"e_1_2_2_47_1","unstructured":"\u00a0"},{"key":"e_1_2_2_48_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja503163k"},{"key":"e_1_2_2_49_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5SC04319K"},{"key":"e_1_2_2_50_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201404946"},{"key":"e_1_2_2_50_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201404946"},{"key":"e_1_2_2_51_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201608937"},{"key":"e_1_2_2_51_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201608937"},{"key":"e_1_2_2_52_1","unstructured":"Examples of the use of a chiral Rh catalyst as the sole catalyst:"},{"key":"e_1_2_2_53_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201206551"},{"key":"e_1_2_2_53_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201206551"},{"key":"e_1_2_2_54_2","unstructured":"see Ref.\u2005[12c];"},{"key":"e_1_2_2_55_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201812937"},{"key":"e_1_2_2_55_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201812937"},{"key":"e_1_2_2_56_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b04756"},{"key":"e_1_2_2_56_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b00278"},{"key":"e_1_2_2_57_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja9823159"},{"key":"e_1_2_2_58_1","unstructured":"CCDC\u20051935197 and 1935297contain the supplementary crystallographic data for this paper. These data can be obtained free of charge fromThe Cambridge Crystallographic Data Centre."},{"key":"e_1_2_2_59_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja9086566"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fanie.201907943","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.201907943","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anie.201907943","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.201907943","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T18:35:41Z","timestamp":1694284541000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201907943"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,14]]},"references-count":70,"journal-issue":{"issue":"39","published-print":{"date-parts":[[2019,9,23]]}},"alternative-id":["10.1002\/anie.201907943"],"URL":"https:\/\/doi.org\/10.1002\/anie.201907943","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,14]]},"assertion":[{"value":"2019-06-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}