{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T02:24:28Z","timestamp":1793154268400,"version":"4.5.0"},"reference-count":75,"publisher":"Wiley","issue":"49","license":[{"start":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T00:00:00Z","timestamp":1571788800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["408295365"],"award-info":[{"award-number":["408295365"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2019,12,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    A titanium\u2010catalyzed mono\u2010decyanation of geminal dinitriles is reported. The reaction proceeds under mild conditions, tolerates numerous functional groups, and can be applied to quaternary malononitriles. A corresponding desulfonylation is demonstrated as well. Mechanistic experiments support a catalyst\u2010controlled cleavage without the formation of free radicals, which is in sharp contrast to traditional stoichiometric radical decyanations. The involvement of two Ti\n                    <jats:sup>III<\/jats:sup>\n                    species in the C\u2212C cleavage is proposed, and the beneficial role of added ZnCl\n                    <jats:sub>2<\/jats:sub>\n                    and 2,4,6\u2010collidine hydrochloride is investigated.\n                  <\/jats:p>","DOI":"10.1002\/anie.201908372","type":"journal-article","created":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T08:45:35Z","timestamp":1568277935000},"page":"17700-17703","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Titanium(III)\u2010Catalyzed Reductive Decyanation of Geminal Dinitriles by a Non\u2010Free\u2010Radical Mechanism"],"prefix":"10.1002","volume":"58","author":[{"given":"Jens","family":"Weweler","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Organische Chemie Albert-Ludwigs-Universit\u00e4t Freiburg  Albertstr. 21 79104 Freiburg im Breisgau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara L.","family":"Younas","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Organische Chemie Albert-Ludwigs-Universit\u00e4t Freiburg  Albertstr. 21 79104 Freiburg im Breisgau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8320-4353","authenticated-orcid":false,"given":"Jan","family":"Streuff","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Organische Chemie Albert-Ludwigs-Universit\u00e4t Freiburg  Albertstr. 21 79104 Freiburg im Breisgau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,10,23]]},"reference":[{"key":"e_1_2_2_1_1","unstructured":"\u00a0"},{"key":"e_1_2_2_2_2","volume-title":"Cleavage of Carbon-Carbon Single Bonds by Transition Metals","year":"2016"},{"key":"e_1_2_2_3_2","volume-title":"Topics in Current Chemistry, Vol.\u2005346","year":"2014"},{"key":"e_1_2_2_4_1","unstructured":"\u00a0"},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b01656"},{"key":"e_1_2_2_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201405067"},{"key":"e_1_2_2_6_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201405067"},{"key":"e_1_2_2_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00138"},{"key":"e_1_2_2_8_2","doi-asserted-by":"publisher","DOI":"10.1039\/B308864M"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201905218"},{"key":"e_1_2_2_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201905218"},{"key":"e_1_2_2_10_1","unstructured":"For reviews on catalytic C\u2212CN cleavage see:"},{"key":"e_1_2_2_11_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5OB01949D"},{"key":"e_1_2_2_12_2","doi-asserted-by":"publisher","DOI":"10.1039\/C4RA08675A"},{"key":"e_1_2_2_13_2","doi-asserted-by":"publisher","DOI":"10.1039\/B702940N"},{"key":"e_1_2_2_14_1","unstructured":"For reviews on reductive decyanations 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Supporting Information."},{"key":"e_1_2_2_61_1","unstructured":"\u00a0"},{"key":"e_1_2_2_62_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8SC04698K"},{"key":"e_1_2_2_63_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201508983"},{"key":"e_1_2_2_63_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201508983"},{"key":"e_1_2_2_64_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja4121567"},{"key":"e_1_2_2_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-328X(01)00892-0"},{"key":"e_1_2_2_66_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja0491230"},{"key":"e_1_2_2_67_1","unstructured":"Owing to the presence of added ZnCl2 the lower limit of the measurement was reduced toE=\u22121.2\u2005V which prevented the detection of [Cp2TiCl2]\u2212."},{"key":"e_1_2_2_68_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja00311a033"},{"key":"e_1_2_2_69_1","unstructured":"[Cp2Ti]+is usually not present in solutions of zinc-reduced Cp2TiCl2but generated during the CV measurement; 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In our case however the presence of ten catalyst equivalents of ZnCl2led to the exclusive formation of [Cp2Ti]+."}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fanie.201908372","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.201908372","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anie.201908372","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.201908372","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T10:48:48Z","timestamp":1694083728000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201908372"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,23]]},"references-count":75,"journal-issue":{"issue":"49","published-print":{"date-parts":[[2019,12,2]]}},"alternative-id":["10.1002\/anie.201908372"],"URL":"https:\/\/doi.org\/10.1002\/anie.201908372","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,23]]},"assertion":[{"value":"2019-07-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}