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This unprecedented olefination process involves a carbene migratory insertion into \u201cCuCF\n                    <jats:sub>3<\/jats:sub>\n                    \u201d to generate the \u03b1\u2010CF\n                    <jats:sub>3<\/jats:sub>\n                    \u2010substituted organocopper species, which then undergoes \u03b2\u2010fluoride elimination and two consecutive addition\u2010elimination processes to give the desired products. The key to this efficient one\u2010pot C\n                    <jats:sub>1<\/jats:sub>\n                    \u2010to\u2010C\n                    <jats:sub>3<\/jats:sub>\n                    synthetic protocol lies in the controllable double (over single and triple) trifluoromethylations of the\n                    <jats:italic>gem\u2010<\/jats:italic>\n                    difluoroalkene intermediates.\n                  <\/jats:p>","DOI":"10.1002\/anie.202002409","type":"journal-article","created":{"date-parts":[[2020,3,2]],"date-time":"2020-03-02T11:05:55Z","timestamp":1583147155000},"page":"8507-8511","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["From C\n                    <sub>1<\/sub>\n                    to C\n                    <sub>3<\/sub>\n                    : Copper\u2010Catalyzed\n                    <i>gem<\/i>\n                    \u2010Bis(trifluoromethyl)olefination of \u03b1\u2010Diazo Esters with TMSCF\n                    <sub>3<\/sub>"],"prefix":"10.1002","volume":"59","author":[{"given":"Qian","family":"Wang","sequence":"first","affiliation":[{"name":"Key Laboratory of Organofluorine Chemistry Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences  345 Ling-Ling Road Shanghai 200032 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanfa","family":"Ni","sequence":"additional","affiliation":[{"name":"Key Laboratory of Organofluorine Chemistry Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences  345 Ling-Ling Road Shanghai 200032 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyou","family":"Hu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Organofluorine Chemistry Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences  345 Ling-Ling Road Shanghai 200032 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiqiang","family":"Xie","sequence":"additional","affiliation":[{"name":"Key Laboratory of Organofluorine Chemistry Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences  345 Ling-Ling Road Shanghai 200032 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinghe","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Organofluorine Chemistry Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences  345 Ling-Ling Road Shanghai 200032 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shitao","family":"Pan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Organofluorine Chemistry Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences  345 Ling-Ling Road Shanghai 200032 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3537-0207","authenticated-orcid":false,"given":"Jinbo","family":"Hu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Organofluorine Chemistry Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences  345 Ling-Ling Road Shanghai 200032 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