{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T19:07:35Z","timestamp":1790363255621,"version":"4.1.0"},"reference-count":191,"publisher":"Wiley","issue":"23","license":[{"start":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T00:00:00Z","timestamp":1609977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Immunotherapy that harnesses the power of the immune system to eliminate malignant cells has offered an effective approach for cancer treatment. However, limited patient response rates and potential immune\u2010related adverse events exist as two major issues for cancer immunotherapy. In parallel, a variety of electromagnetic nanomaterials that generate heat and\/or reactive oxygen species triggered by electromagnetic energy have been applied for magnetic hyperthermia therapy, sonodynamic therapy, photothermal therapy, photodynamic therapy, and radiotherapy, which have the ability to induce immunogenic cell death. This review summarizes the recent development of electromagnetic nanomedicines in combinational cancer immunotherapy. The mechanisms of electromagnetic nanomedicines in reprogramming the immunosuppressive tumor microenvironment and sensitizing tumors for cancer immunotherapy are highlighted. Furthermore, potential challenges and perspectives of electromagnetic nanomedicines for combinational cancer immunotherapy are discussed.<\/jats:p>","DOI":"10.1002\/anie.202008386","type":"journal-article","created":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T23:30:45Z","timestamp":1594855845000},"page":"12682-12705","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":204,"title":["Electromagnetic Nanomedicines for Combinational Cancer Immunotherapy"],"prefix":"10.1002","volume":"60","author":[{"given":"Jingchao","family":"Li","sequence":"first","affiliation":[{"name":"School of Chemical and Biomedical Engineering Nanyang Technological University  70 Nanyang Drive Singapore 637457 Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Luo","sequence":"additional","affiliation":[{"name":"School of Chemical Science and Engineering Tongji University  1239 Siping Road Shanghai 200092 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8064-6009","authenticated-orcid":false,"given":"Kanyi","family":"Pu","sequence":"additional","affiliation":[{"name":"School of Chemical and Biomedical Engineering Nanyang Technological University  70 Nanyang Drive Singapore 637457 Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,7]]},"reference":[{"key":"e_1_2_10_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1566"},{"key":"e_1_2_10_2_1","unstructured":"\u00a0"},{"key":"e_1_2_10_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3958"},{"key":"e_1_2_10_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf2784"},{"key":"e_1_2_10_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2016.128"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-019-0108-1"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4822"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0010-1"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3239"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0269-6"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2014.111"},{"key":"e_1_2_10_12_1","unstructured":"\u00a0"},{"key":"e_1_2_10_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrc.2016.36"},{"key":"e_1_2_10_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13954"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2017.148"},{"key":"e_1_2_10_16_1","unstructured":"\u00a0"},{"key":"e_1_2_10_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2016.58"},{"key":"e_1_2_10_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2016.205"},{"key":"e_1_2_10_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2017.144"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6CS00458J"},{"key":"e_1_2_10_21_1","unstructured":"\u00a0"},{"key":"e_1_2_10_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmat3776"},{"key":"e_1_2_10_23_2","doi-asserted-by":"publisher","DOI":"10.1039\/C9CS00773C"},{"key":"e_1_2_10_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202004397"},{"key":"e_1_2_10_25_1","unstructured":"\u00a0"},{"key":"e_1_2_10_26_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8CS00896E"},{"key":"e_1_2_10_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201804882"},{"key":"e_1_2_10_27_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201804882"},{"key":"e_1_2_10_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201903394"},{"key":"e_1_2_10_29_1","unstructured":"\u00a0"},{"key":"e_1_2_10_30_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.9b00148"},{"key":"e_1_2_10_31_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3380"},{"key":"e_1_2_10_32_1","unstructured":"\u00a0"},{"key":"e_1_2_10_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-018-0007-y"},{"key":"e_1_2_10_34_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-019-0308-z"},{"key":"e_1_2_10_35_1","unstructured":"\u00a0"},{"key":"e_1_2_10_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2011.95"},{"key":"e_1_2_10_37_2","doi-asserted-by":"publisher","DOI":"10.1038\/natrevmats.2017.20"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200700091"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar200090c"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9CS00648F"},{"key":"e_1_2_10_41_1","unstructured":"\u00a0"},{"key":"e_1_2_10_42_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b11846"},{"key":"e_1_2_10_43_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b08225"},{"key":"e_1_2_10_44_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201602012"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/cas.13578"},{"key":"e_1_2_10_46_1","unstructured":"\u00a0"},{"key":"e_1_2_10_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2009.326"},{"key":"e_1_2_10_48_2","doi-asserted-by":"publisher","DOI":"10.1038\/86684"},{"key":"e_1_2_10_49_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-016-0010"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2016.05.022"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00594F"},{"key":"e_1_2_10_52_1","unstructured":"\u00a0"},{"key":"e_1_2_10_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2010.01.140"},{"key":"e_1_2_10_54_2","doi-asserted-by":"publisher","DOI":"10.1039\/b108586g"},{"key":"e_1_2_10_55_1","unstructured":"\u00a0"},{"key":"e_1_2_10_56_2","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.14425"},{"key":"e_1_2_10_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03473-9"},{"key":"e_1_2_10_58_2","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201800678"},{"key":"e_1_2_10_59_1","unstructured":"\u00a0"},{"key":"e_1_2_10_60_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21324"},{"key":"e_1_2_10_61_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncponc0486"},{"key":"e_1_2_10_62_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1950"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7MH00451F"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-019-0238-9"},{"key":"e_1_2_10_65_1","unstructured":"\u00a0"},{"key":"e_1_2_10_66_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2016.211"},{"key":"e_1_2_10_67_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-020-0246-1"},{"key":"e_1_2_10_68_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0232-2"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2017.1365953"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2003.tb01438.x"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b01979"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b08550"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.9b00579"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b08320"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201901690"},{"key":"e_1_2_10_76_1","first-page":"4589","volume":"34","author":"Inui T.","year":"2014","journal-title":"Anticancer Res."},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201901335"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09760-3"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201907953"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201704408"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201701439"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.9b02903"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201908185"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.06.003"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.06.065"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119629"},{"key":"e_1_2_10_87_1","unstructured":"\u00a0"},{"key":"e_1_2_10_88_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.09.014"},{"key":"e_1_2_10_89_2","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201700805"},{"key":"e_1_2_10_90_2","doi-asserted-by":"publisher","DOI":"10.1039\/C9NR09402D"},{"key":"e_1_2_10_91_2","doi-asserted-by":"publisher","DOI":"10.7150\/thno.19826"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119370"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2020.124314"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201402996"},{"key":"e_1_2_10_95_1","unstructured":"\u00a0"},{"key":"e_1_2_10_96_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b07371"},{"key":"e_1_2_10_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.01.027"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2016.10.015"},{"key":"e_1_2_10_99_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b01107"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b06040"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.43604"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.07.035"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b17137"},{"key":"e_1_2_10_104_1","unstructured":"\u00a0"},{"key":"e_1_2_10_105_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13193"},{"key":"e_1_2_10_106_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8NR05323E"},{"key":"e_1_2_10_107_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b05876"},{"key":"e_1_2_10_108_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-020-0160-6"},{"key":"e_1_2_10_109_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b00204"},{"key":"e_1_2_10_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.06.031"},{"key":"e_1_2_10_111_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201900004"},{"key":"e_1_2_10_112_1","unstructured":"\u00a0"},{"key":"e_1_2_10_113_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201906623"},{"key":"e_1_2_10_114_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03915-4"},{"key":"e_1_2_10_115_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12771-9"},{"key":"e_1_2_10_116_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201803001"},{"key":"e_1_2_10_117_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201700891"},{"key":"e_1_2_10_118_1","unstructured":"\u00a0"},{"key":"e_1_2_10_119_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b18751"},{"key":"e_1_2_10_120_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.119933"},{"key":"e_1_2_10_121_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-018-0236-8"},{"key":"e_1_2_10_122_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0127-6"},{"key":"e_1_2_10_123_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201901240"},{"key":"e_1_2_10_124_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b02993"},{"key":"e_1_2_10_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119515"},{"key":"e_1_2_10_126_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.9b02448"},{"key":"e_1_2_10_127_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-018-0147-9"},{"key":"e_1_2_10_128_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b04736"},{"key":"e_1_2_10_129_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201802479"},{"key":"e_1_2_10_130_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201900499"},{"key":"e_1_2_10_131_1","unstructured":"\u00a0"},{"key":"e_1_2_10_132_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b07045"},{"key":"e_1_2_10_133_2","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201900996"},{"key":"e_1_2_10_134_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201905758"},{"key":"e_1_2_10_135_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b06691"},{"key":"e_1_2_10_136_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b09538"},{"key":"e_1_2_10_137_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b04315"},{"key":"e_1_2_10_138_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b00040"},{"key":"e_1_2_10_139_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201902440"},{"key":"e_1_2_10_140_1","unstructured":"\u00a0"},{"key":"e_1_2_10_141_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms12499"},{"key":"e_1_2_10_142_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-01050-0"},{"key":"e_1_2_10_143_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b12788"},{"key":"e_1_2_10_144_1","unstructured":"\u00a0"},{"key":"e_1_2_10_145_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201911429"},{"key":"e_1_2_10_145_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201911429"},{"key":"e_1_2_10_146_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201900927"},{"key":"e_1_2_10_147_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b00715"},{"key":"e_1_2_10_148_1","unstructured":"\u00a0"},{"key":"e_1_2_10_149_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.6b01994"},{"key":"e_1_2_10_150_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.11.019"},{"key":"e_1_2_10_151_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201707249"},{"key":"e_1_2_10_152_1","unstructured":"\u00a0"},{"key":"e_1_2_10_153_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.9b04012"},{"key":"e_1_2_10_154_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b09112"},{"key":"e_1_2_10_155_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b06663"},{"key":"e_1_2_10_156_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.03.027"},{"key":"e_1_2_10_157_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201903332"},{"key":"e_1_2_10_158_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201902960"},{"key":"e_1_2_10_159_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11269-8"},{"key":"e_1_2_10_160_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.03.020"},{"key":"e_1_2_10_161_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201905825"},{"key":"e_1_2_10_162_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201802157"},{"key":"e_1_2_10_163_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201904997"},{"key":"e_1_2_10_164_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201906288"},{"key":"e_1_2_10_164_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201906288"},{"key":"e_1_2_10_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.02.036"},{"key":"e_1_2_10_166_1","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2017.113"},{"key":"e_1_2_10_167_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b02720"},{"key":"e_1_2_10_168_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201802228"},{"key":"e_1_2_10_169_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04703-w"},{"key":"e_1_2_10_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matt.2019.06.007"},{"key":"e_1_2_10_171_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b08962"},{"key":"e_1_2_10_172_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-018-0203-4"},{"key":"e_1_2_10_173_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd4663"},{"key":"e_1_2_10_174_1","unstructured":"\u00a0"},{"key":"e_1_2_10_175_2","first-page":"11","volume":"6","author":"Miller A. C.","year":"2014","journal-title":"Virus Adapt. Treat."},{"key":"e_1_2_10_176_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcyt.2017.02.002"},{"key":"e_1_2_10_177_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40169-018-0214-5"},{"key":"e_1_2_10_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2016.07.005"},{"key":"e_1_2_10_179_1","unstructured":"\u00a0"},{"key":"e_1_2_10_180_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201906314"},{"key":"e_1_2_10_181_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c00659"},{"key":"e_1_2_10_182_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-019-0378-4"},{"key":"e_1_2_10_183_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3987"},{"key":"e_1_2_10_184_1","unstructured":"\u00a0"},{"key":"e_1_2_10_185_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201901607"},{"key":"e_1_2_10_186_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8CS00001H"},{"key":"e_1_2_10_187_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.9b00569"},{"key":"e_1_2_10_188_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-019-0508-y"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fanie.202008386","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202008386","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anie.202008386","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202008386","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,27]],"date-time":"2023-08-27T23:03:57Z","timestamp":1693177437000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.202008386"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,7]]},"references-count":191,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1002\/anie.202008386"],"URL":"https:\/\/doi.org\/10.1002\/anie.202008386","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,7]]},"assertion":[{"value":"2020-06-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}