{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:06:49Z","timestamp":1790712409628,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"50","license":[{"start":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T00:00:00Z","timestamp":1601596800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003006","name":"Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003006","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2020,12,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Fluorinated organophosphorus(V) compounds are a very versatile class of compounds, but the synthetic methods available to make them bear the disadvantages of 1)\u2005occasional handling of toxic or pyrophoric P\n                    <jats:sup>III<\/jats:sup>\n                    starting materials and 2)\u2005a dependence on hazardous fluorinating reagents such as XeF\n                    <jats:sub>2<\/jats:sub>\n                    . Herein, we present a simple solution and introduce a deoxygenative fluorination (DOF) approach that utilizes easy\u2010to\u2010handle phosphine oxides as starting materials and effectively replaces harsh fluorinating reagents by a combination of oxalyl chloride and potassium fluoride. The reaction has proven to be general, as R\n                    <jats:sub>3<\/jats:sub>\n                    PF\n                    <jats:sub>2<\/jats:sub>\n                    , R\n                    <jats:sub>2<\/jats:sub>\n                    PF\n                    <jats:sub>3<\/jats:sub>\n                    , and RPF\n                    <jats:sub>4<\/jats:sub>\n                    compounds (as well as various cations and anions derived from these) are accessible in good yields and on up to a multi\u2010gram scale. DFT calculations were used to bolster our observations. Notably, the discovery of this new method led to a convenient synthesis of 1)\u2005new difluorophosphonium ions, 2)\u2005hexafluorophosphate salts, and 3)\u2005fluorinated antimony\u2010 and arsenic\u2010 compounds.\n                  <\/jats:p>","DOI":"10.1002\/anie.202010943","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T13:30:17Z","timestamp":1598535017000},"page":"22790-22795","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Deoxygenative Fluorination of Phosphine Oxides: A General Route to Fluorinated Organophosphorus(V) Compounds and Beyond"],"prefix":"10.1002","volume":"59","author":[{"given":"Dustin","family":"Bornemann","sequence":"first","affiliation":[{"name":"Department of Chemistry and Applied Biosciences ETH Z\u00fcrich  Vladimir-Prelog-Weg 2 8093 Z\u00fcrich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cody Ross","family":"Pitts","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Applied Biosciences ETH Z\u00fcrich  Vladimir-Prelog-Weg 2 8093 Z\u00fcrich Switzerland"},{"name":"The Scripps Research Institute  10550 N. 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La Jolla CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lionel","family":"Wettstein","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Applied Biosciences ETH Z\u00fcrich  Vladimir-Prelog-Weg 2 8093 Z\u00fcrich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Br\u00fcning","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Applied Biosciences ETH Z\u00fcrich  Vladimir-Prelog-Weg 2 8093 Z\u00fcrich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"K\u00fcng","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Applied Biosciences ETH Z\u00fcrich  Vladimir-Prelog-Weg 2 8093 Z\u00fcrich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangyu","family":"Guan","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Applied Biosciences ETH Z\u00fcrich  Vladimir-Prelog-Weg 2 8093 Z\u00fcrich Switzerland"},{"name":"The Scripps Research Institute  10550 N. 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