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The aim of this treatment was to initiate the lysis of fibrin; however, there are many side\u2010effects associated with this form of treatment. Herein, we fabricated chiral Co\n                    <jats:sub>3<\/jats:sub>\n                    O\n                    <jats:sub>4<\/jats:sub>\n                    supraparticles (SPs) with a g\u2010factor of up to 0.02 at 550\u2005nm and paramagnetic performance applied in the treatment of thromboembolism under an electromagnetic field (MF). In vitro experiments showed that\n                    <jats:sc>d<\/jats:sc>\n                    \u2010SPs degraded blood clot within 8\u2005hours under MF. Compared to\n                    <jats:sc>l<\/jats:sc>\n                    \u2010SPs,\n                    <jats:sc>d<\/jats:sc>\n                    \u2010SPs exhibited much stronger thrombolytic ability and effectively enhanced the survival rate of thrombosis model mice more than 70\u2009% in the 25\u2005d of observation. The results of mechanism study showed that under MF, the level of reactive oxygen species (ROS) produced by\n                    <jats:sc>d<\/jats:sc>\n                    \u2010SPs were 1.5 times higher than that of\n                    <jats:sc>l<\/jats:sc>\n                    \u2010SPs, which might be attributed to the chiral\u2010induced spin selectivity effects.\n                  <\/jats:p>","DOI":"10.1002\/anie.202105675","type":"journal-article","created":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T05:10:41Z","timestamp":1621573841000},"page":"18240-18246","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Improved Reactive Oxygen Species Generation by Chiral Co\n                    <sub>3<\/sub>\n                    O\n                    <sub>4<\/sub>\n                    Supraparticles under Electromagnetic Fields"],"prefix":"10.1002","volume":"60","author":[{"given":"Xiuxiu","family":"Wang","sequence":"first","affiliation":[{"name":"Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering State Key Laboratory of Food Science and Technology International Joint Research Laboratory for Biointerface and Biodetection, School of Food Science and Technology Jiangnan University  Wuxi Jiangsu 214122 China"},{"name":"International Joint Research Laboratory for Biointerface and Biodetection Jiangnan University  Wuxi Jiangsu 214122 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maozhong","family":"Sun","sequence":"additional","affiliation":[{"name":"Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering State Key Laboratory of Food Science and Technology International Joint Research Laboratory for Biointerface and Biodetection, School of Food Science 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