{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:56:40Z","timestamp":1790704600064,"version":"4.1.0"},"reference-count":66,"publisher":"Wiley","issue":"37","license":[{"start":{"date-parts":[[2021,8,8]],"date-time":"2021-08-08T00:00:00Z","timestamp":1628380800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2021,9,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The acyl nitroso Diels\u2013Alder reaction of 1,3\u2010dienes with electrochemically oxidised hydroxamic acids is described. By using alternating current electrolysis, their typical electro\u2010induced decomposition could be suppressed in favour of the 1,2\u2010oxazine cycloaddition products. The reaction was optimised using Design of Experiments (DoE) and a sensitivity test was conducted. A mixture of triethylamine\/hexafluoroisopropanol served as supporting electrolyte in dichloromethane, thus giving products of high purity after evaporation of the volatiles without further purification. The optimised reaction conditions were applied to various 1,3\u2010dienes and hydroxamic acids, giving up to 96\u2009% isolated yield.<\/jats:p>","DOI":"10.1002\/anie.202107148","type":"journal-article","created":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T18:09:00Z","timestamp":1625681340000},"page":"20313-20317","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Alternating Current Electrolysis as Efficient Tool for the Direct Electrochemical Oxidation of Hydroxamic Acids for Acyl Nitroso Diels\u2013Alder Reactions"],"prefix":"10.1002","volume":"60","author":[{"given":"Jan","family":"F\u00e4hrmann","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Chemie Universit\u00e4t Oldenburg Carl-von-Ossietzky-Stra\u00dfe 9\u201311 26111 Oldenburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5279-3378","authenticated-orcid":false,"given":"Gerhard","family":"Hilt","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Chemie Universit\u00e4t Oldenburg Carl-von-Ossietzky-Stra\u00dfe 9\u201311 26111 Oldenburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,8,8]]},"reference":[{"key":"e_1_2_2_1_1","unstructured":"For selected reviews see:"},{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202001654"},{"key":"e_1_2_2_2_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202001654"},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5RA17488K"},{"key":"e_1_2_2_4_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr300436a"},{"key":"e_1_2_2_5_1","unstructured":"For selected reviews see:"},{"key":"e_1_2_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s41061-016-0026-2"},{"key":"e_1_2_2_7_2","volume-title":"Hetero Diels\u2013Alder Methodology in Organic Synthesis","author":"Boger D. 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