{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:01:00Z","timestamp":1772118060990,"version":"3.50.1"},"reference-count":118,"publisher":"Wiley","issue":"42","license":[{"start":{"date-parts":[[2021,9,15]],"date-time":"2021-09-15T00:00:00Z","timestamp":1631664000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R35GM133438"],"award-info":[{"award-number":["R35GM133438"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2021,10,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We report a Ni\u2010catalyzed regioselective arylbenzylation of alkenylarenes with benzyl halides and arylzinc reagents. The reaction furnishes differently substituted 1,1,3\u2010triarylpropyl structures that are reminiscent of the cores of oligoresveratrol natural products. The reaction is also compatible for the coupling of internal alkenes, secondary benzyl halides and variously substituted arylzinc reagents. Kinetic studies reveal that the reaction proceeds with a rate\u2010limiting single\u2010electron\u2010transfer process and is autocatalyzed by in\u2010situ\u2010generated ZnX\n                    <jats:sub>2<\/jats:sub>\n                    . The reaction rate is amplified by a factor of three through autocatalysis upon addition of ZnX\n                    <jats:sub>2<\/jats:sub>\n                    .\n                  <\/jats:p>","DOI":"10.1002\/anie.202110459","type":"journal-article","created":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T10:28:02Z","timestamp":1629800882000},"page":"22977-22982","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Ni\u2010Catalyzed Arylbenzylation of Alkenylarenes: Kinetic Studies Reveal Autocatalysis by ZnX\n                    <sub>2<\/sub>\n                    **"],"prefix":"10.1002","volume":"60","author":[{"given":"Roshan K.","family":"Dhungana","sequence":"first","affiliation":[{"name":"Department of Chemistry Pennsylvania State University  University Park Pennsylvania 16802 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rishi R.","family":"Sapkota","sequence":"additional","affiliation":[{"name":"Department of Chemistry Pennsylvania State University  University Park Pennsylvania 16802 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura M.","family":"Wickham","sequence":"additional","affiliation":[{"name":"Department of Chemistry Pennsylvania State University  University Park Pennsylvania 16802 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doleshwar","family":"Niroula","sequence":"additional","affiliation":[{"name":"Department of Chemistry Pennsylvania State University  University Park Pennsylvania 16802 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bijay","family":"Shrestha","sequence":"additional","affiliation":[{"name":"Current address: Department of Chemistry and Biochemistry University of California  Los Angeles CA 90095 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8993-9131","authenticated-orcid":false,"given":"Ramesh","family":"Giri","sequence":"additional","affiliation":[{"name":"Department of Chemistry Pennsylvania State University  University Park Pennsylvania 16802 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,15]]},"reference":[{"key":"e_1_2_6_1_1","unstructured":"For reviews see:"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/tcr.201700098"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.7b03128"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1039\/C9SC06006E"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2020.05.013"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.0c02115"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/ar990095d"},{"key":"e_1_2_6_8_1","unstructured":"\u00a0"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf6123"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aad6080"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja983066r"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol303003g"},{"key":"e_1_2_6_13_1","unstructured":"\u00a0"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.7b02072"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1087339"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201813148"},{"key":"e_1_2_6_16_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201813148"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.9b00774"},{"key":"e_1_2_6_18_1","unstructured":"\u00a0"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1039\/C7SC03149A"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1039\/C7SC04351A"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.0c03857"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b09401"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b03163"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.9b03574"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja201358b"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol4023358"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201913062"},{"key":"e_1_2_6_27_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201913062"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b11942"},{"key":"e_1_2_6_29_1","unstructured":"\u00a0"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8SC01735B"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c09778"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201913435"},{"key":"e_1_2_6_32_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201913435"},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c08823"},{"key":"e_1_2_6_34_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c08532"},{"key":"e_1_2_6_35_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b06567"},{"key":"e_1_2_6_36_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c09922"},{"key":"e_1_2_6_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201915837"},{"key":"e_1_2_6_37_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201915837"},{"key":"e_1_2_6_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2019.12.026"},{"key":"e_1_2_6_39_1","unstructured":"\u00a0"},{"key":"e_1_2_6_40_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b03195"},{"key":"e_1_2_6_41_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b02973"},{"key":"e_1_2_6_42_2","doi-asserted-by":"publisher","DOI":"10.1039\/D0SC02127J"},{"key":"e_1_2_6_43_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b08282"},{"key":"e_1_2_6_44_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201908029"},{"key":"e_1_2_6_44_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201908029"},{"key":"e_1_2_6_45_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b07194"},{"key":"e_1_2_6_46_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c03210"},{"key":"e_1_2_6_47_1","unstructured":"\u00a0"},{"key":"e_1_2_6_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202008498"},{"key":"e_1_2_6_48_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202008498"},{"key":"e_1_2_6_49_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201606458"},{"key":"e_1_2_6_49_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201606458"},{"key":"e_1_2_6_50_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05951-6"},{"key":"e_1_2_6_51_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c03708"},{"key":"e_1_2_6_52_1","unstructured":"For alkene dicarbofunctionalization by cyclization\/coupling see:"},{"key":"e_1_2_6_53_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201912746"},{"key":"e_1_2_6_53_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201912746"},{"key":"e_1_2_6_54_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202004439"},{"key":"e_1_2_6_54_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202004439"},{"key":"e_1_2_6_55_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202006439"},{"key":"e_1_2_6_55_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202006439"},{"key":"e_1_2_6_56_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201911012"},{"key":"e_1_2_6_56_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201911012"},{"key":"e_1_2_6_57_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201903353"},{"key":"e_1_2_6_57_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201903353"},{"key":"e_1_2_6_58_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b01258"},{"key":"e_1_2_6_59_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.oprd.9b00248"},{"key":"e_1_2_6_60_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b12554"},{"key":"e_1_2_6_61_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201901067"},{"key":"e_1_2_6_61_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201901067"},{"key":"e_1_2_6_62_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b08190"},{"key":"e_1_2_6_63_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201913367"},{"key":"e_1_2_6_63_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201913367"},{"key":"e_1_2_6_64_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.0c00297"},{"key":"e_1_2_6_65_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.9b01620"},{"key":"e_1_2_6_66_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b09245"},{"key":"e_1_2_6_67_1","unstructured":"\u00a0"},{"key":"e_1_2_6_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2012.04.064"},{"key":"e_1_2_6_69_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201308666"},{"key":"e_1_2_6_69_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201308666"},{"key":"e_1_2_6_70_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.oprd.9b00199"},{"key":"e_1_2_6_71_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm960517e"},{"key":"e_1_2_6_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0896(01)00038-4"},{"key":"e_1_2_6_73_1","unstructured":"\u00a0"},{"key":"e_1_2_6_74_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11418-018-1266-y"},{"key":"e_1_2_6_75_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10600-017-2049-5"},{"key":"e_1_2_6_76_2","doi-asserted-by":"publisher","DOI":"10.1021\/np058064g"},{"key":"e_1_2_6_77_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201713165"},{"key":"e_1_2_6_77_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201713165"},{"key":"e_1_2_6_78_1","unstructured":"\u00a0"},{"key":"e_1_2_6_79_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b05374"},{"key":"e_1_2_6_80_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c09008"},{"key":"e_1_2_6_81_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8CC07587E"},{"key":"e_1_2_6_82_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8CC06509H"},{"key":"e_1_2_6_83_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b06608"},{"key":"e_1_2_6_84_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b00915"},{"key":"e_1_2_6_85_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b01036"},{"key":"e_1_2_6_86_1","unstructured":"\u00a0"},{"key":"e_1_2_6_87_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b06340"},{"key":"e_1_2_6_88_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b05680"},{"key":"e_1_2_6_89_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201900228"},{"key":"e_1_2_6_89_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201900228"},{"key":"e_1_2_6_90_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200900218"},{"key":"e_1_2_6_90_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200900218"},{"key":"e_1_2_6_91_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b00775"},{"key":"e_1_2_6_92_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b09909"},{"key":"e_1_2_6_93_1","unstructured":"For mechanisms of Ni-catalyzed alkene difunctionalization reactions see:"},{"key":"e_1_2_6_94_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b10026"},{"key":"e_1_2_6_95_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.0c00032"},{"key":"e_1_2_6_96_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c02355"},{"key":"e_1_2_6_97_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja063334i"},{"key":"e_1_2_6_98_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.5b00057"},{"key":"e_1_2_6_99_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-14016-1"},{"key":"e_1_2_6_100_1","doi-asserted-by":"publisher","DOI":"10.1021\/om00002a005"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202110459","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anie.202110459","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202110459","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,27]],"date-time":"2023-08-27T09:17:15Z","timestamp":1693127835000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.202110459"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,15]]},"references-count":118,"journal-issue":{"issue":"42","published-print":{"date-parts":[[2021,10,11]]}},"alternative-id":["10.1002\/anie.202110459"],"URL":"https:\/\/doi.org\/10.1002\/anie.202110459","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.26434\/chemrxiv-2021-0nw8q","asserted-by":"object"}]},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,15]]},"assertion":[{"value":"2021-08-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}