{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:49:50Z","timestamp":1792525790793,"version":"4.5.0"},"reference-count":184,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T00:00:00Z","timestamp":1645574400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22125104 and 21831007"],"award-info":[{"award-number":["22125104 and 21831007"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20201018"],"award-info":[{"award-number":["BK20201018"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2022,4,19]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The first highly atroposelective construction of N\u2212N axially chiral indole scaffolds was established via a new strategy of de novo ring formation. This strategy makes use of the organocatalytic asymmetric Paal\u2013Knorr reaction of well\u2010designed <jats:italic>N<\/jats:italic>\u2010aminoindoles with 1,4\u2010diketones, thus affording <jats:italic>N<\/jats:italic>\u2010pyrrolylindoles in high yields and with excellent atroposelectivities (up to 98\u2009% yield, 96\u2009% ee). In addition, this strategy is applicable for the atroposelective synthesis of N\u2212N axially chiral bispyrroles (up to 98\u2009% yield, 97\u2009% ee). More importantly, such N\u2212N axially chiral heterocycles can be converted into chiral organocatalysts with applications in asymmetric catalysis, and some molecules display potent anticancer activity. This work not only provides a new strategy for the atroposelective synthesis of N\u2212N axially chiral molecules but also offers new members of the N\u2212N atropisomer family with promising applications in synthetic and medicinal chemistry.<\/jats:p>","DOI":"10.1002\/anie.202116829","type":"journal-article","created":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T15:44:55Z","timestamp":1643211895000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":175,"title":["Organocatalytic Atroposelective Synthesis of N\u2212N Axially Chiral Indoles and Pyrroles by De Novo Ring Formation"],"prefix":"10.1002","volume":"61","author":[{"given":"Ke\u2010Wei","family":"Chen","sequence":"first","affiliation":[{"name":"School of Chemistry and Materials Science Jiangsu Normal University  Xuzhou 221116 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi\u2010Han","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Chemistry and Materials Science Jiangsu Normal University  Xuzhou 221116 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Materials Science Jiangsu Normal University  Xuzhou 221116 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu\u2010Fang","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Chemistry and Materials Science Jiangsu Normal University  Xuzhou 221116 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Chen","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Materials Science Jiangsu Normal University  Xuzhou 221116 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3922-0708","authenticated-orcid":false,"given":"Feng","family":"Shi","sequence":"additional","affiliation":[{"name":"School of Chemistry and Materials Science Jiangsu Normal University  Xuzhou 221116 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,2,23]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr100155e"},{"key":"e_1_2_7_2_1","unstructured":"For reviews:"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm200584g"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.4155\/fmc-2017-0152"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/9783527635207"},{"key":"e_1_2_7_6_1","unstructured":"For reviews:"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00146"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00136"},{"key":"e_1_2_7_9_1","unstructured":"For recent reviews:"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1039\/C7CC06863H"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201800078"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.7b00602"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.6023\/cjoc201904030"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC03967H"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1360\/SSC-2019-0168"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/cjoc.202000751"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS00870B"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c01306"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1706028"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gresc.2021.12.005"},{"key":"e_1_2_7_21_1","unstructured":"For a prominent work:"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1188403"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b01458"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201508419"},{"key":"e_1_2_7_24_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201508419"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201606063"},{"key":"e_1_2_7_25_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201606063"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201710537"},{"key":"e_1_2_7_26_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201710537"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201701849"},{"key":"e_1_2_7_27_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201701849"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.8b01037"},{"key":"e_1_2_7_29_1","unstructured":"For recent examples of six-membered heterobiaryls:"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201509967"},{"key":"e_1_2_7_30_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201509967"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201605486"},{"key":"e_1_2_7_31_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201605486"},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201801824"},{"key":"e_1_2_7_32_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201801824"},{"key":"e_1_2_7_33_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201902126"},{"key":"e_1_2_7_33_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201902126"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202002208"},{"key":"e_1_2_7_34_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202002208"},{"key":"e_1_2_7_35_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b07972"},{"key":"e_1_2_7_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201713200"},{"key":"e_1_2_7_36_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201713200"},{"key":"e_1_2_7_37_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b05819"},{"key":"e_1_2_7_38_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b03862"},{"key":"e_1_2_7_39_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b12858"},{"key":"e_1_2_7_40_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c08205"},{"key":"e_1_2_7_41_1","unstructured":"For recent examples of five-membered heterobiaryls:"},{"key":"e_1_2_7_42_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b11079"},{"key":"e_1_2_7_43_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.8b04870"},{"key":"e_1_2_7_44_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201812654"},{"key":"e_1_2_7_44_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201812654"},{"key":"e_1_2_7_45_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b08510"},{"key":"e_1_2_7_46_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.9b00767"},{"key":"e_1_2_7_47_1","unstructured":"For recent examples of aryl alkenes via asymmetric organocatalysis:"},{"key":"e_1_2_7_48_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms15238"},{"key":"e_1_2_7_49_2","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2710"},{"key":"e_1_2_7_50_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b03211"},{"key":"e_1_2_7_51_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b09893"},{"key":"e_1_2_7_52_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41929-019-0278-7"},{"key":"e_1_2_7_53_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c00208"},{"key":"e_1_2_7_54_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201915470"},{"key":"e_1_2_7_54_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201915470"},{"key":"e_1_2_7_55_1","unstructured":"For recent examples of aryl alkenes via asymmetric metal-catalysis:"},{"key":"e_1_2_7_56_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201509571"},{"key":"e_1_2_7_56_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201509571"},{"key":"e_1_2_7_57_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201701467"},{"key":"e_1_2_7_57_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201701467"},{"key":"e_1_2_7_58_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201915949"},{"key":"e_1_2_7_58_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201915949"},{"key":"e_1_2_7_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2019.12.011"},{"key":"e_1_2_7_60_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c04400"},{"key":"e_1_2_7_61_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c06236"},{"key":"e_1_2_7_62_1","unstructured":"For recent examples of aryl quinoids:"},{"key":"e_1_2_7_63_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12269-4"},{"key":"e_1_2_7_64_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202004671"},{"key":"e_1_2_7_64_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202004671"},{"key":"e_1_2_7_65_2","doi-asserted-by":"publisher","DOI":"10.1002\/cjoc.202000131"},{"key":"e_1_2_7_66_2","doi-asserted-by":"publisher","DOI":"10.1002\/cjoc.202100214"},{"key":"e_1_2_7_67_1","unstructured":"For examples of aryl amides:"},{"key":"e_1_2_7_68_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13189"},{"key":"e_1_2_7_69_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201602689"},{"key":"e_1_2_7_69_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201602689"},{"key":"e_1_2_7_70_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201814362"},{"key":"e_1_2_7_70_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201814362"},{"key":"e_1_2_7_71_1","unstructured":"For recent examples ofN-aryl heteroaryls:"},{"key":"e_1_2_7_72_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b09634"},{"key":"e_1_2_7_73_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b01911"},{"key":"e_1_2_7_74_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-10858-x"},{"key":"e_1_2_7_75_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201914876"},{"key":"e_1_2_7_75_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201914876"},{"key":"e_1_2_7_76_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202108747"},{"key":"e_1_2_7_76_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202108747"},{"key":"e_1_2_7_77_1","unstructured":"For recent examples of anilides:"},{"key":"e_1_2_7_78_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b06014"},{"key":"e_1_2_7_79_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.8b04789"},{"key":"e_1_2_7_80_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.9b05443"},{"key":"e_1_2_7_81_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c09400"},{"key":"e_1_2_7_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10677"},{"key":"e_1_2_7_83_1","unstructured":"For recent examples of imides:"},{"key":"e_1_2_7_84_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201901619"},{"key":"e_1_2_7_84_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201901619"},{"key":"e_1_2_7_85_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.1c02450"},{"key":"e_1_2_7_86_1","unstructured":"For recent examples of quinazolinones:"},{"key":"e_1_2_7_87_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b07726"},{"key":"e_1_2_7_88_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms15489"},{"key":"e_1_2_7_89_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b11303"},{"key":"e_1_2_7_90_1","unstructured":"For a recent example of pyridinones:"},{"key":"e_1_2_7_91_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b01738"},{"key":"e_1_2_7_92_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b12994"},{"key":"e_1_2_7_93_1","unstructured":"For examples:"},{"key":"e_1_2_7_94_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2005.07.047"},{"key":"e_1_2_7_95_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201200599"},{"key":"e_1_2_7_96_2","doi-asserted-by":"publisher","DOI":"10.1021\/np400124n"},{"key":"e_1_2_7_97_1","unstructured":"For examples:"},{"key":"e_1_2_7_98_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm9506433"},{"key":"e_1_2_7_99_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2018.06.050"},{"key":"e_1_2_7_100_1","unstructured":"For examples:"},{"key":"e_1_2_7_101_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-328X(96)06682-X"},{"key":"e_1_2_7_102_2","doi-asserted-by":"publisher","DOI":"10.1080\/10426509908546267"},{"key":"e_1_2_7_103_1","volume-title":"Chemistry,","author":"Chang R.","year":"2012"},{"key":"e_1_2_7_104_1","unstructured":"\u00a0"},{"key":"e_1_2_7_105_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2021.07.013"},{"key":"e_1_2_7_106_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c07741"},{"key":"e_1_2_7_107_1","unstructured":"\u00a0"},{"key":"e_1_2_7_108_2","doi-asserted-by":"publisher","DOI":"10.1039\/D1SC05360D"},{"key":"e_1_2_7_109_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.1c04028"},{"key":"e_1_2_7_110_1","unstructured":"For examples:"},{"key":"e_1_2_7_111_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201908279"},{"key":"e_1_2_7_111_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201908279"},{"key":"e_1_2_7_112_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201806294"},{"key":"e_1_2_7_112_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201806294"},{"key":"e_1_2_7_113_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c02519"},{"key":"e_1_2_7_114_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202001397"},{"key":"e_1_2_7_115_1","unstructured":"For examples of 3-(hetero)arylindoles:"},{"key":"e_1_2_7_116_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201608150"},{"key":"e_1_2_7_116_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201608150"},{"key":"e_1_2_7_117_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.7b01855"},{"key":"e_1_2_7_118_2","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2866"},{"key":"e_1_2_7_119_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201811177"},{"key":"e_1_2_7_119_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201811177"},{"key":"e_1_2_7_120_2","doi-asserted-by":"publisher","DOI":"10.1002\/cjoc.202000022"},{"key":"e_1_2_7_121_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2020.06.001"},{"key":"e_1_2_7_122_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-021-00750-x"},{"key":"e_1_2_7_123_2","doi-asserted-by":"publisher","DOI":"10.1039\/D1SC05161J"},{"key":"e_1_2_7_124_2","first-page":"10","author":"Wu P.","year":"2022","journal-title":"Fund. Res."},{"key":"e_1_2_7_125_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-28211-0"},{"key":"e_1_2_7_126_1","unstructured":"For examples of 2-arylindoles:"},{"key":"e_1_2_7_127_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b04711"},{"key":"e_1_2_7_128_2","doi-asserted-by":"publisher","DOI":"10.1039\/C9SC00810A"},{"key":"e_1_2_7_129_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201908961"},{"key":"e_1_2_7_129_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201908961"},{"key":"e_1_2_7_130_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201914049"},{"key":"e_1_2_7_130_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201914049"},{"key":"e_1_2_7_131_2","doi-asserted-by":"publisher","DOI":"10.31635\/ccschem.021.202101154"},{"key":"e_1_2_7_132_1","unstructured":"For examples ofN-arylindoles:"},{"key":"e_1_2_7_133_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201000243"},{"key":"e_1_2_7_134_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202000585"},{"key":"e_1_2_7_134_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202000585"},{"key":"e_1_2_7_135_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202012932"},{"key":"e_1_2_7_135_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202012932"},{"key":"e_1_2_7_136_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202111860"},{"key":"e_1_2_7_136_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202111860"},{"key":"e_1_2_7_137_1","unstructured":"For a summary:"},{"key":"e_1_2_7_138_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.9b00549"},{"key":"e_1_2_7_139_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201901955"},{"key":"e_1_2_7_139_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201901955"},{"key":"e_1_2_7_140_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202011267"},{"key":"e_1_2_7_140_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202011267"},{"key":"e_1_2_7_141_1","unstructured":"For reviews:"},{"key":"e_1_2_7_142_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr068374j"},{"key":"e_1_2_7_143_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1218801"},{"key":"e_1_2_7_144_2","doi-asserted-by":"publisher","DOI":"10.1021\/ar2000343"},{"key":"e_1_2_7_145_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr5001496"},{"key":"e_1_2_7_146_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8CS00436F"},{"key":"e_1_2_7_147_1","unstructured":"For early reports:"},{"key":"e_1_2_7_148_2","doi-asserted-by":"publisher","DOI":"10.1002\/cber.188401702228"},{"key":"e_1_2_7_149_2","doi-asserted-by":"publisher","DOI":"10.1002\/cber.188401702254"},{"key":"e_1_2_7_150_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202112226"},{"key":"e_1_2_7_150_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202112226"},{"key":"e_1_2_7_151_1","unstructured":"Deposition Numbers2127161 and 2127162contains the supplementary crystallographic data for this paper. These data are provided free of charge by the joint Cambridge Crystallographic Data Centre and Fachinformationszentrum KarlsruheAccess Structures service."}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202116829","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anie.202116829","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202116829","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T05:46:07Z","timestamp":1729662367000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.202116829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,23]]},"references-count":184,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2022,4,19]]}},"alternative-id":["10.1002\/anie.202116829"],"URL":"https:\/\/doi.org\/10.1002\/anie.202116829","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,23]]},"assertion":[{"value":"2021-12-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202116829"}}