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Experimental and DFT mechanistic studies highlight the complexity of the cross\u2010electrophile coupling and provide insight into the sequence of the three consecutive oxidative additions of aryl halide, chloroformate, and alkyl halide.<\/jats:p>","DOI":"10.1002\/anie.202204144","type":"journal-article","created":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T18:07:28Z","timestamp":1655834848000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":73,"title":["Reactivity in Nickel\u2010Catalyzed Multi\u2010component Sequential Reductive Cross\u2010Coupling Reactions"],"prefix":"10.1002","volume":"61","author":[{"given":"Haifeng","family":"Chen","sequence":"first","affiliation":[{"name":"KAUST Catalysis Center (KCC) King Abdullah University of Science and Technology (KAUST)  Thuwal 23955-6900 Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huifeng","family":"Yue","sequence":"additional","affiliation":[{"name":"KAUST Catalysis Center (KCC) King Abdullah University of Science and Technology (KAUST)  Thuwal 23955-6900 Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Zhu","sequence":"additional","affiliation":[{"name":"KAUST Catalysis Center (KCC) King Abdullah University of Science and Technology (KAUST)  Thuwal 23955-6900 Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4580-5227","authenticated-orcid":false,"given":"Magnus","family":"Rueping","sequence":"additional","affiliation":[{"name":"KAUST Catalysis Center (KCC) King Abdullah University of Science and Technology (KAUST)  Thuwal 23955-6900 Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,11]]},"reference":[{"key":"e_1_2_7_1_1","unstructured":"\u00a0"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13274"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo500507s"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.5b00057"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5QO00224A"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00162"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s41061-016-0042-2"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf7230"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.7b00212"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-017-0065"},{"key":"e_1_2_7_11_2","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/9783527813827.ch9","volume-title":"Nickel Catalysis in Synthesis: Methods and Reactions, Vol.\u2005352","author":"Goldfogel M. 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