{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T02:21:43Z","timestamp":1791598903261,"version":"4.3.4"},"reference-count":34,"publisher":"Wiley","issue":"30","license":[{"start":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T00:00:00Z","timestamp":1684281600000},"content-version":"am","delay-in-days":349,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#am"},{"start":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:00:00Z","timestamp":1654128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["F32-GM139372"],"award-info":[{"award-number":["F32-GM139372"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1R35GM126961"],"award-info":[{"award-number":["1R35GM126961"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CHE-2107602"],"award-info":[{"award-number":["CHE-2107602"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2022,7,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    S\/N crosstalk species derived from the interconnected reactivity of H\n                    <jats:sub>2<\/jats:sub>\n                    S and NO facilitate the transport of reactive sulfur and nitrogen species in signaling, transport, and regulatory processes. We report here that simple Fe\n                    <jats:sup>2+<\/jats:sup>\n                    ions, such as those that are bioavailable in the labile iron pool (LIP), react with thionitrite (SNO\n                    <jats:sup>\u2212<\/jats:sup>\n                    ) and perthionitrite (SSNO\n                    <jats:sup>\u2212<\/jats:sup>\n                    ) to yield the dinitrosyl iron complex [Fe(NO)\n                    <jats:sub>2<\/jats:sub>\n                    (S\n                    <jats:sub>5<\/jats:sub>\n                    )]\n                    <jats:sup>\u2212<\/jats:sup>\n                    . In the reaction of FeCl\n                    <jats:sub>2<\/jats:sub>\n                    with SNO\n                    <jats:sup>\u2212<\/jats:sup>\n                    we were able to isolate the unstable intermediate hydrosulfido mononitrosyl iron complex [FeCl\n                    <jats:sub>2<\/jats:sub>\n                    (NO)(SH)]\n                    <jats:sup>\u2212<\/jats:sup>\n                    , which was characterized by X\u2010ray crystallography. We also show that [Fe(NO)\n                    <jats:sub>2<\/jats:sub>\n                    (S\n                    <jats:sub>5<\/jats:sub>\n                    )]\n                    <jats:sup>\u2212<\/jats:sup>\n                    is a simple synthon for nitrosylated Fe\u2212S clusters via its reduction with PPh\n                    <jats:sub>3<\/jats:sub>\n                    to yield Roussin's Red Salt ([Fe\n                    <jats:sub>2<\/jats:sub>\n                    S\n                    <jats:sub>2<\/jats:sub>\n                    (NO)\n                    <jats:sub>4<\/jats:sub>\n                    ]\n                    <jats:sup>2\u2212<\/jats:sup>\n                    ), which highlights the role of S\/N crosstalk species in the assembly of fundamental Fe\u2212S motifs.\n                  <\/jats:p>","DOI":"10.1002\/anie.202204570","type":"journal-article","created":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T14:04:00Z","timestamp":1652796240000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Thionitrite (SNO\n                    <sup>\u2212<\/sup>\n                    ) and Perthionitrite (SSNO\n                    <sup>\u2212<\/sup>\n                    ) are Simple Synthons for Nitrosylated Iron Sulfur Clusters"],"prefix":"10.1002","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2205-1370","authenticated-orcid":false,"given":"Tobias J.","family":"Sherbow","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry Materials Science Institute Knight Campus for Accelerating Scientific Impact and Institute of Molecular Biology University of Oregon  Eugene OR 97403\u20131253 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Chemistry University of California Davis  Davis CA 95616 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lizhi","family":"Tao","sequence":"additional","affiliation":[{"name":"Department of Chemistry University of California Davis  Davis CA 95616 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lev N.","family":"Zakharov","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry Materials Science Institute Knight Campus for Accelerating Scientific Impact and Institute of Molecular Biology University of Oregon  Eugene OR 97403\u20131253 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. David","family":"Britt","sequence":"additional","affiliation":[{"name":"Department of Chemistry University of California Davis  Davis CA 95616 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3604-653X","authenticated-orcid":false,"given":"Michael D.","family":"Pluth","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry Materials Science Institute Knight Campus for Accelerating Scientific Impact and Institute of Molecular Biology University of Oregon  Eugene OR 97403\u20131253 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,2]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2016.6909"},{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja3009693"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1509277112"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2006.02.003"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b03456"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202104906"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202104906"},{"key":"e_1_2_7_7_1","first-page":"477","volume":"139","author":"Playfair L.","year":"1849","journal-title":"Proc. R. Soc. London"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201503353"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm3012036"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.niox.2018.03.003"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar500459j"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.49.29244"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(02)01006-7"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.1c00823"},{"key":"e_1_2_7_15_1","unstructured":"Using fewer than 3\u2005equiv of [PNP][SSNO] also provided [PNP][Fe(NO)2(S5)] albeit in lower yields."},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/ic0494915"},{"key":"e_1_2_7_17_1","unstructured":"The\u03c44parameter uses the bond angels of four-coordinate complexes as a metric to deteremine how close to a perfect tetrahedral or square planar molecular geometry the complex is. A\u03c44of 0 indicates a perfect square planar complex whereas a\u03c44of 1 indicates a perfect tetrahedral complex."},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1039\/B617136B"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2012.05.007"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja510393q"},{"key":"e_1_2_7_21_1","unstructured":"\u00a0"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja503683y"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.1c00429"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9CS00570F"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/ic501765g"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-8545(00)80259-3"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b08053"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja0293599"},{"key":"e_1_2_7_29_1","unstructured":"To test if THF was the source of the H atom we synthesized2from both THF andd8-THF and acquired EPR data on the resultant products. These results were inconclusive because we were unable to see conclusive differences in the continuous-wave (CW) EPR spectra of the two samples (Figure\u2005S3)."},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.0c02622"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.6b01660"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201305669"},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201305669"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202204570","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anie.202204570","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/am-pdf\/10.1002\/anie.202204570","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202204570","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T02:20:03Z","timestamp":1692843603000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.202204570"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,2]]},"references-count":34,"journal-issue":{"issue":"30","published-print":{"date-parts":[[2022,7,25]]}},"alternative-id":["10.1002\/anie.202204570"],"URL":"https:\/\/doi.org\/10.1002\/anie.202204570","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.742154644.793593460","asserted-by":"object"}]},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,2]]},"assertion":[{"value":"2022-03-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202204570"}}