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Complex\n                    <jats:bold>2<\/jats:bold>\n                    was able to difluoromethylate a variety of electrophiles including electron\u2010deficient and electron\u2010rich aryl iodides, heteroaryl iodides, activated heteroaryl bromides, chloride and aryl bromides with a directing group, as well as other electrophiles such as alkenyl iodide, benzyl bromides, allyl bromides, alkyl iodide, allyl carbonates and acid chloride. In addition, in the presence of an oxidant, complex\n                    <jats:bold>2<\/jats:bold>\n                    reacted with various lithium\n                    <jats:italic>n<\/jats:italic>\n                    butyl arylboronic acid pinacol esters, alkyne and heteroarene. Moreover, complex\n                    <jats:bold>2<\/jats:bold>\n                    could transmetalate the difluoromethyl reagent to other metals such as [Ph\n                    <jats:sub>4<\/jats:sub>\n                    P]\n                    <jats:sup>+<\/jats:sup>\n                    [CuCl\n                    <jats:sub>2<\/jats:sub>\n                    ]\n                    <jats:sup>\u2212<\/jats:sup>\n                    and [(DPPF)PdCl\n                    <jats:sub>2<\/jats:sub>\n                    ].\n                  <\/jats:p>","DOI":"10.1002\/anie.202210151","type":"journal-article","created":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T22:39:30Z","timestamp":1661726370000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["[Ph\n                    <sub>4<\/sub>\n                    P]\n                    <sup>+<\/sup>\n                    [Cu(CF\n                    <sub>2<\/sub>\n                    H)\n                    <sub>2<\/sub>\n                    ]\n                    <sup>\u2212<\/sup>\n                    : A Powerful Difluoromethylating Reagent Inspired by Mechanistic Investigation"],"prefix":"10.1002","volume":"61","author":[{"given":"Haiwei","family":"Zhao","sequence":"first","affiliation":[{"name":"Key Laboratory of Organofluorine Chemistry Shanghai Institute of Organic Chemistry 345 Lingling Lu Shanghai 200032 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuebing B.","family":"Leng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Organofluorine Chemistry Shanghai Institute of Organic Chemistry 345 Lingling Lu Shanghai 200032 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Centre for Green Chemistry and Department of Chemistry University of Massachusetts Boston 100 Morrissey Boulevard Boston Massachusetts 02125 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