{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T20:34:55Z","timestamp":1792874095794,"version":"4.5.0"},"reference-count":95,"publisher":"Wiley","issue":"41","license":[{"start":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T00:00:00Z","timestamp":1662422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2022R1A2C3004731"],"award-info":[{"award-number":["NRF-2022R1A2C3004731"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2022,10,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Reported herein is the efficient synthesis of tetra\u2010 and tri\u2010substituted (<jats:italic>Z<\/jats:italic>)\u2010fluoro\u2010 and (<jats:italic>Z<\/jats:italic>)\u2010chloro\u2010borylalkenes by the Boron\u2013Wittig reaction of ketones and aldehydes with bench\u2010top stable halo\u2010diborylmethanes. The substrate scope is broad and the Boron\u2013Wittig reaction proceeds from a diverse range of ketones and aldehydes including biologically relevant molecules with fluoro\u2010 or chloro\u2010diborylmethanes, providing tetra\u2010 and tri\u2010substituted (<jats:italic>Z<\/jats:italic>)\u2010fluoro\u2010 and (<jats:italic>Z<\/jats:italic>)\u2010chloro\u2010borylalkenes in good yields with high stereoselectivity. The utilities of the obtained (<jats:italic>Z<\/jats:italic>)\u2010fluoro\u2010 and (<jats:italic>Z<\/jats:italic>)\u2010chloro\u2010borylalkenes are highlighted by further modifications to afford fluoroalkene derivatives or all\u2010carbon substituted alkene.<\/jats:p>","DOI":"10.1002\/anie.202210532","type":"journal-article","created":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T15:30:53Z","timestamp":1661268653000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Stereoselective Access to Tetra\u2010 and Tri\u2010Substituted Fluoro\u2010 and Chloro\u2010Borylalkenes via Boron\u2010Wittig Reaction"],"prefix":"10.1002","volume":"61","author":[{"given":"Seungcheol","family":"Han","sequence":"first","affiliation":[{"name":"Department of Chemistry Pohang University of Science and Technology (POSTECH) Pohang 37673 Republic of 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