{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:17:47Z","timestamp":1790295467903,"version":"4.1.0"},"reference-count":62,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,29]],"date-time":"2022-11-29T00:00:00Z","timestamp":1669680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["91753126, 21622207"],"award-info":[{"award-number":["91753126, 21622207"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012247","name":"Program of Shanghai Academic Research Leader","doi-asserted-by":"publisher","award":["21XD1424700"],"award-info":[{"award-number":["21XD1424700"]}],"id":[{"id":"10.13039\/501100012247","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2023,1,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The aldehydes installation by radical formylation constitutes an attractive synthetic strategy. However, the generation of formyl radicals for organic synthesis applications remains unknown. Herein we report the first formyl radical generation from \u03b1\u2010chloro\n                    <jats:italic>N<\/jats:italic>\n                    \u2010methoxyphthalimides, which selectively synthesize aldehydes by alkene hydroformylation under mild photoredox conditions. The aldehydes can be installed on acrylates, acrylamides, vinyl sulfones, vinyl ketones, and complex steroids by radical hydroformylation in excellent chemoselectivity and regioselectivity. The concerted hydrochloride elimination for the formyl radical generation from \u03b1\u2010chloro methoxy radicals is established by experimental and computational approaches.\n                  <\/jats:p>","DOI":"10.1002\/anie.202213686","type":"journal-article","created":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T10:25:50Z","timestamp":1667816750000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Formyl Radical Generation from \u03b1\u2010Chloro\n                    <i>N<\/i>\n                    \u2010Methoxyphthalimides Enables Selective Aldehyde Synthesis"],"prefix":"10.1002","volume":"62","author":[{"given":"Dan","family":"Liu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Bioorganic and Natural Products Chemistry Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences  345 Lingling Road Shanghai 200032 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Yang","sequence":"additional","affiliation":[{"name":"Green Catalysis Center College of Chemistry Zhengzhou University  Zhengzhou Henan, 450001 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Fang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioorganic and Natural Products Chemistry Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences  345 Lingling Road Shanghai 200032 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi\u2010Jun","family":"Li","sequence":"additional","affiliation":[{"name":"Green Catalysis Center College of Chemistry Zhengzhou University  Zhengzhou Henan, 450001 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Lan","sequence":"additional","affiliation":[{"name":"Green Catalysis Center College of Chemistry Zhengzhou University  Zhengzhou Henan, 450001 China"},{"name":"School of Chemistry and Chemical Engineering Chongqing Key Laboratory of Theoretical and Computational Chemistry Chongqing University  Chongqing 400030 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0916-0994","authenticated-orcid":false,"given":"Yiyun","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioorganic and Natural Products Chemistry Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences  345 Lingling Road Shanghai 200032 China"},{"name":"School of Physical Science and Technology ShanghaiTech University  100 Haike Road Shanghai 201210 China"},{"name":"School of Chemistry and Material Sciences Hangzhou Institute for Advanced Study University of Chinese Academy of Sciences  1 Sub-lane Xiangshan Hangzhou 310024 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