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Their surface is chemically tailored to respond to analytes by a change in fluorescence. However, intensity\u2010based signals are easily affected by external factors such as sample movements. Here, we demonstrate fluorescence lifetime imaging microscopy (FLIM) of SWCNT\u2010based sensors in the NIR. We tailor a confocal laser scanning microscope (CLSM) for NIR signals (&gt;800\u2005nm) and employ time correlated single photon counting of (GT)\n                    <jats:sub>10<\/jats:sub>\n                    \u2010DNA functionalized SWCNTs. They act as sensors for the important neurotransmitter dopamine. Their fluorescence lifetime (&gt;900\u2005nm) decays biexponentially and the longer lifetime component (370\u2005ps) increases by up to 25\u2009% with dopamine concentration. These sensors serve as paint to cover cells and report extracellular dopamine in 3D via FLIM. Therefore, we demonstrate the potential of fluorescence lifetime as a readout of SWCNT\u2010based NIR sensors.\n                  <\/jats:p>","DOI":"10.1002\/anie.202300682","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T04:20:15Z","timestamp":1678335615000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Near\u2010Infrared Fluorescence Lifetime Imaging of Biomolecules with Carbon Nanotubes**"],"prefix":"10.1002","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6465-866X","authenticated-orcid":false,"given":"Linda","family":"Sistemich","sequence":"first","affiliation":[{"name":"Physical Chemistry II Ruhr-University Bochum  Universit\u00e4tsstr. 150 44801 Bochum 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