{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T02:48:43Z","timestamp":1789267723184,"version":"build-2803163510"},"reference-count":83,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T00:00:00Z","timestamp":1679875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21772122"],"award-info":[{"award-number":["21772122"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai","doi-asserted-by":"publisher","award":["22ZR1445200"],"award-info":[{"award-number":["22ZR1445200"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018558","name":"Shanghai Shuguang Program","doi-asserted-by":"publisher","award":["20SG44"],"award-info":[{"award-number":["20SG44"]}],"id":[{"id":"10.13039\/501100018558","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2023,4,24]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Organic nitrates are broadly applied as pharmaceuticals (acting as efficient nitric oxide donor), energetic materials, building blocks in organic synthesis, etc. However, practical and direct methods to access organic nitrates efficiently are still rare, mainly due to the lack of powerful nitrooxylating reagents. Herein, we report bench\u2010stable and highly reactive noncyclic hypervalent iodine nitrooxylating reagents, oxybis(aryl\u2010\u03bb<jats:sup>3<\/jats:sup>\u2010iodanediyl) dinitrates (OAIDNs, <jats:bold>2<\/jats:bold>), which are prepared just by using aryliodine diacetate and HNO<jats:sub>3<\/jats:sub>. The reagents are used to achieve a mild and operationally simple protocol to access diverse organic nitrates. By employing of <jats:bold>2<\/jats:bold>, zinc\u2010catalyzed regioselective nitrooxylation of cyclopropyl silyl ethers is realized efficiently to access the corresponding \u03b2\u2010nitrooxy ketones with high functional\u2010group tolerance. Moreover, a series of direct and catalyst\u2010free nitrooxylations of enolizable C\u2212H bonds are carried out smoothly to afford the desired organic nitrates within minutes by just mixing the substrates with <jats:bold>2<\/jats:bold> in dichloromethane.<\/jats:p>","DOI":"10.1002\/anie.202302521","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T10:51:21Z","timestamp":1678359081000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Simple and Versatile Nitrooxylation: Noncyclic Hypervalent Iodine Nitrooxylating Reagent"],"prefix":"10.1002","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1545-6567","authenticated-orcid":false,"given":"Xuan","family":"Cheng","sequence":"first","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry Shanghai Key Laboratory of Rare Earth Functional Materials and Shanghai Frontiers Science Center of Biomimetic Catalysis Shanghai Normal University  Shanghai 200234 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan","family":"Yin","sequence":"additional","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry Shanghai Key Laboratory of Rare Earth Functional Materials and Shanghai Frontiers Science Center of Biomimetic Catalysis Shanghai Normal University  Shanghai 200234 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Xuan","family":"Jiang","sequence":"additional","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry Shanghai Key Laboratory of Rare Earth Functional Materials and Shanghai Frontiers Science Center of Biomimetic Catalysis Shanghai Normal University  Shanghai 200234 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling\u2010Feng","family":"Jiang","sequence":"additional","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry Shanghai Key Laboratory of Rare Earth Functional Materials and Shanghai Frontiers Science Center of Biomimetic Catalysis Shanghai Normal University  Shanghai 200234 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si\u2010Yuan","family":"Li","sequence":"additional","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry Shanghai Key Laboratory of Rare Earth Functional Materials and Shanghai Frontiers Science Center of Biomimetic Catalysis Shanghai Normal University  Shanghai 200234 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi\u2010Fei","family":"Cheng","sequence":"additional","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry Shanghai Key Laboratory of Rare Earth Functional Materials and Shanghai Frontiers Science Center of Biomimetic Catalysis Shanghai Normal University  Shanghai 200234 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin\u2010Chang","family":"Sun","sequence":"additional","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry Shanghai Key Laboratory of Rare Earth Functional Materials and Shanghai Frontiers Science Center of Biomimetic Catalysis Shanghai Normal University  Shanghai 200234 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lujun","family":"Peng","sequence":"additional","affiliation":[{"name":"College of Chemistry and Molecular Sciences Wuhan University  Wuhan Hubei 430072 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Zhong","sequence":"additional","affiliation":[{"name":"College of Chemistry and Molecular Sciences Wuhan University  Wuhan Hubei 430072 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7793-1434","authenticated-orcid":false,"given":"Qing\u2010Hai","family":"Deng","sequence":"additional","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry Shanghai Key Laboratory of Rare Earth Functional Materials and Shanghai Frontiers Science Center of Biomimetic Catalysis Shanghai Normal University  Shanghai 200234 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,27]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1470903"},{"key":"e_1_2_7_2_1","unstructured":"Selected reviews on notric oxide 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Regulations UN Recommendations on the Transport of Dangerous Goods Manual of Tests and Criteria 5th\u2005edn. United Nations Publication New York 2009; according to UN recommendations on the transport of dangerous goods: impact insensitive >40\u2005J less sensitive \u226535\u2005J sensitive \u22654\u2005J very sensitive \u22643\u2005J; friction insensitive >360\u2005N less sensitive 360\u2005N 80\u2005N <sensitive <360\u2005N very sensitive <80\u2005N extremely sensitive <10\u2005N."},{"key":"e_1_2_7_64_1","unstructured":"Deposition numbers\u20052024938 (for2\u2009a) 2130176 (for6\u2009a) and 2130175 (for31)contain the supplementary crystallographic data for this paper. 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