{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T10:05:23Z","timestamp":1791540323378,"version":"4.3.4"},"reference-count":90,"publisher":"Wiley","issue":"26","license":[{"start":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T00:00:00Z","timestamp":1683244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2023,6,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    How to transfer industrial exhaust gases of nitrogen oxides into high\u2010values product is significantly important and challenging. Herein, we demonstrate an innovative method for artificial synthesis of essential \u03b1\u2010amino acids from nitric oxide (NO) by reacting with \u03b1\u2010keto acids through electrocatalytic process with atomically dispersed Fe supported on N\u2010doped carbon matrix (AD\u2010Fe\/NC) as the catalyst. A yield of valine with 32.1\u2005\u03bcmol\u2009mg\n                    <jats:sub>cat<\/jats:sub>\n                    <jats:sup>\u22121<\/jats:sup>\n                    is delivered at \u22120.6\u2005V\n                    <jats:italic>vs<\/jats:italic>\n                    . reversible hydrogen electrode, corresponding a selectivity of 11.3\u2009%. In situ X\u2010ray absorption fine structure and synchrotron radiation infrared spectroscopy analyses show that NO as nitrogen source converted to hydroxylamine that promptly nucleophilic attacked on the electrophilic carbon center of \u03b1\u2010keto acid to form oxime and subsequent reductive hydrogenation occurred on the way to amino acid. Over 6 kinds of \u03b1\u2010amino acids have been successfully synthesized and gaseous nitrogen source can be also replaced by liquid nitrogen source (NO\n                    <jats:sub>3<\/jats:sub>\n                    <jats:sup>\u2212<\/jats:sup>\n                    ). Our findings not only provide a creative method for converting nitrogen oxides into high\u2010valued products, which is of epoch\u2010making significance towards artificial synthesis of amino acids, but also benefit in deploying near\u2010zero\u2010emission technologies for global environmental and economic development.\n                  <\/jats:p>","DOI":"10.1002\/anie.202304007","type":"journal-article","created":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T22:19:33Z","timestamp":1681856373000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":223,"title":["Electrocatalytic Synthesis of Essential Amino Acids from Nitric Oxide Using Atomically Dispersed Fe on N\u2010doped Carbon"],"prefix":"10.1002","volume":"62","author":[{"given":"Jiahui","family":"Xian","sequence":"first","affiliation":[{"name":"MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional Materials School of Chemistry Sun Yat-Sen University  Guangzhou 510006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suisheng","family":"Li","sequence":"additional","affiliation":[{"name":"MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional Materials School of Chemistry Sun Yat-Sen University  Guangzhou 510006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Su","sequence":"additional","affiliation":[{"name":"National Synchrotron Radiation Laboratory University of Science and Technology of China  Hefei 230029 China"},{"name":"Key Laboratory of Light Energy Conversion Materials of Hunan Province College College of Chemistry and Chemical Engineering Hunan Normal University  Changsha 410081 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peisen","family":"Liao","sequence":"additional","affiliation":[{"name":"MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional Materials School of Chemistry Sun Yat-Sen University  Guangzhou 510006 China"},{"name":"School of Chemistry and Environment Jiaying University  Meizhou 514015 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shihan","family":"Wang","sequence":"additional","affiliation":[{"name":"MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional Materials School of Chemistry Sun Yat-Sen University  Guangzhou 510006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yawei","family":"Zhang","sequence":"additional","affiliation":[{"name":"MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional Materials School of Chemistry Sun Yat-Sen University  Guangzhou 510006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqian","family":"Yang","sequence":"additional","affiliation":[{"name":"MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional Materials School of Chemistry Sun Yat-Sen University  Guangzhou 510006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Yang","sequence":"additional","affiliation":[{"name":"MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional Materials School of Chemistry Sun Yat-Sen University  Guangzhou 510006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yamei","family":"Sun","sequence":"additional","affiliation":[{"name":"MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional Materials School of Chemistry Sun Yat-Sen University  Guangzhou 510006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaling","family":"Jia","sequence":"additional","affiliation":[{"name":"MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional Materials School of Chemistry Sun Yat-Sen University  Guangzhou 510006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinglin","family":"Liu","sequence":"additional","affiliation":[{"name":"MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional Materials School of Chemistry Sun Yat-Sen University  Guangzhou 510006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinghua","family":"Liu","sequence":"additional","affiliation":[{"name":"National Synchrotron Radiation Laboratory University of Science and Technology of China  Hefei 230029 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1233-5591","authenticated-orcid":false,"given":"Guangqin","family":"Li","sequence":"additional","affiliation":[{"name":"MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional Materials School of Chemistry Sun Yat-Sen University  Guangzhou 510006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,5]]},"reference":[{"key":"e_1_2_7_1_1","unstructured":"\u00a0"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2780-0"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41893-017-0003-y"},{"key":"e_1_2_7_4_1","unstructured":"\u00a0"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s43017-020-0063-9"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2019.02.005"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41558-019-0665-8"},{"key":"e_1_2_7_8_1","unstructured":"\u00a0"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-20867-w"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-019-0356-0"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.136712"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.684"},{"key":"e_1_2_7_13_1","unstructured":"\u00a0"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/ees.2017.0516"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rser.2021.111916"},{"key":"e_1_2_7_16_1","unstructured":"\u00a0"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41929-021-00640-y"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202101522"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41560-020-00709-1"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/sus2.7"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/nenergy.2015.6"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c04981"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2018.05.003"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsenergylett.1c02471"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/s44160-022-00193-3"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c10714"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-022-00379-5"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201906915"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apcatb.2018.11.084"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apcatb.2021.120750"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC07208J"},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11426-021-1173-8"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2019.111826"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8CS00665B"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-020-0176-1"},{"key":"e_1_2_7_36_1","unstructured":"\u00a0"},{"key":"e_1_2_7_37_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40820-021-00768-3"},{"key":"e_1_2_7_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202110186"},{"key":"e_1_2_7_39_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c01649"},{"key":"e_1_2_7_40_2","doi-asserted-by":"publisher","DOI":"10.1002\/cey2.73"},{"key":"e_1_2_7_41_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b13341"},{"key":"e_1_2_7_42_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.0c05092"},{"key":"e_1_2_7_43_2","doi-asserted-by":"publisher","DOI":"10.1021\/accountsmr.2c00041"},{"key":"e_1_2_7_44_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.2c00847"},{"key":"e_1_2_7_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2019.122591"},{"key":"e_1_2_7_46_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202210871"},{"key":"e_1_2_7_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-13907-7"},{"key":"e_1_2_7_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201910987"},{"key":"e_1_2_7_49_1","unstructured":"\u00a0"},{"key":"e_1_2_7_50_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.119.315626"},{"key":"e_1_2_7_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-74022-y"},{"key":"e_1_2_7_52_1","unstructured":"\u00a0"},{"key":"e_1_2_7_53_2","doi-asserted-by":"publisher","DOI":"10.1039\/C4CS90059F"},{"key":"e_1_2_7_54_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201703663"},{"key":"e_1_2_7_55_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.9b00842"},{"key":"e_1_2_7_56_2","doi-asserted-by":"publisher","DOI":"10.1002\/aenm.202100321"},{"key":"e_1_2_7_57_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1181761"},{"key":"e_1_2_7_58_2","doi-asserted-by":"publisher","DOI":"10.1039\/b903811f"},{"key":"e_1_2_7_59_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2738-2"},{"key":"e_1_2_7_60_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.0c04898"},{"key":"e_1_2_7_61_2","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.add5678"},{"key":"e_1_2_7_62_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.0c00512"},{"key":"e_1_2_7_63_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201712872"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2017.224"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201103433"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201811126"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2515"},{"key":"e_1_2_7_68_1","unstructured":"\u00a0"},{"key":"e_1_2_7_69_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202113895"},{"key":"e_1_2_7_70_2","doi-asserted-by":"publisher","DOI":"10.1039\/D2NH00143H"},{"key":"e_1_2_7_71_1","unstructured":"\u00a0"},{"key":"e_1_2_7_72_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b09352"},{"key":"e_1_2_7_73_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202000896"},{"key":"e_1_2_7_74_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202004534"},{"key":"e_1_2_7_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-23115-x"},{"key":"e_1_2_7_76_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201803262"},{"key":"e_1_2_7_77_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevB.71.094110"},{"key":"e_1_2_7_78_1","unstructured":"\u00a0"},{"key":"e_1_2_7_79_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2014.09.048"},{"key":"e_1_2_7_80_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2022.214766"},{"key":"e_1_2_7_81_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201607426"},{"key":"e_1_2_7_82_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.0c03018"},{"key":"e_1_2_7_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41560-018-0308-8"},{"key":"e_1_2_7_84_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7TA08746B"},{"key":"e_1_2_7_85_1","unstructured":"\u00a0"},{"key":"e_1_2_7_86_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-34169-w"},{"key":"e_1_2_7_87_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-020-0481-9"},{"key":"e_1_2_7_88_1","unstructured":"\u00a0"},{"key":"e_1_2_7_89_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202015773"},{"key":"e_1_2_7_90_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c01950"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202304007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T12:59:59Z","timestamp":1704373199000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.202304007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,5]]},"references-count":90,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2023,6,26]]}},"alternative-id":["10.1002\/anie.202304007"],"URL":"https:\/\/doi.org\/10.1002\/anie.202304007","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,5]]},"assertion":[{"value":"2023-03-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202304007"}}