{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:28:09Z","timestamp":1790886489911,"version":"4.1.0"},"reference-count":97,"publisher":"Wiley","issue":"32","license":[{"start":{"date-parts":[[2023,6,29]],"date-time":"2023-06-29T00:00:00Z","timestamp":1687996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100010446","name":"Institute for Basic Science","doi-asserted-by":"publisher","award":["IBS-R010-A2"],"award-info":[{"award-number":["IBS-R010-A2"]}],"id":[{"id":"10.13039\/501100010446","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2023,8,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Considering the prevalence of alcohols and carboxylic acids, their fragment cross\u2010coupling reactions could hold significant implications in organic synthesis. Herein, we report a versatile method for synthesizing a diverse range of ketones from alcohols and carboxylic acid derivatives via <jats:italic>N<\/jats:italic>\u2010heterocyclic carbene (NHC) catalysis. Mechanistic investigations revealed that photoexcited xanthates and acyl azoliums undergo single electron transfer (SET) under photocatalyst\u2010free conditions, generating NHC\u2010derived ketyl radicals and alkyl radicals. These open\u2010shell intermediates subsequently undergo the radical\u2010radical cross\u2010coupling reaction, yielding valuable ketones. Furthermore, this approach can be employed in three\u2010component reactions involving alkenes and enynes, resulting in structurally diverse cross\u2010coupled ketones. The unified strategy offers a unique opportunity for the fragment coupling of a diverse range of alcohols and carboxylic acid derivatives, accommodating diverse functional groups even in complex settings.<\/jats:p>","DOI":"10.1002\/anie.202306191","type":"journal-article","created":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T09:35:16Z","timestamp":1686562516000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Photoinduced Electron Transfer from Xanthates to Acyl Azoliums: Divergent Ketone Synthesis via <i>N<\/i>\u2010Heterocyclic Carbene Catalysis"],"prefix":"10.1002","volume":"62","author":[{"given":"Chang\u2010Yin","family":"Tan","sequence":"first","affiliation":[{"name":"Department of Chemistry Korea Advanced Institute of Science and Technology (KAIST)  Daejeon 34141 Republic of Korea"},{"name":"Center for Catalytic Hydrocarbon Functionalizations Institute for Basic Science (IBS)  Daejeon 34141 Republic 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