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H\n                    <jats:sub>2<\/jats:sub>\n                    S overproduction has been linked to a variety of disease states and therefore, H\n                    <jats:sub>2<\/jats:sub>\n                    S\u2010depleting agents, such as scavengers, are needed to understand the significance of H\n                    <jats:sub>2<\/jats:sub>\n                    S\u2010based therapy. It is known that elevated H\n                    <jats:sub>2<\/jats:sub>\n                    S can induce oxidative stress with elevated reactive oxygen species (ROS) formation, such as in H\n                    <jats:sub>2<\/jats:sub>\n                    S acute intoxication. We explored the possibility of developing catalytic scavengers to simultaneously remove H\n                    <jats:sub>2<\/jats:sub>\n                    S and ROS. Herein, we studied a series of selenium\u2010based molecules as catalytic H\n                    <jats:sub>2<\/jats:sub>\n                    S\/H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    scavengers. Inspired by the high reactivity of selenoxide compounds towards H\n                    <jats:sub>2<\/jats:sub>\n                    S, 14 diselenide\/monoselenide compounds were tested. Several promising candidates such as\n                    <jats:bold>S6<\/jats:bold>\n                    were identified. Their activities in buffers, as well as in plasma\u2010 and cell lysate\u2010containing solutions were evaluated. We also studied the reaction mechanism of this scavenging process. Finally, the combination of the diselenide catalyst and photosensitizers was used to achieve light\u2010induced H\n                    <jats:sub>2<\/jats:sub>\n                    S removal. These Se\u2010based scavengers can be useful tools for understanding H\n                    <jats:sub>2<\/jats:sub>\n                    S\/ROS regulations.\n                  <\/jats:p>","DOI":"10.1002\/anie.202317487","type":"journal-article","created":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T16:20:59Z","timestamp":1702657259000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Selenium\u2010Based Catalytic Scavengers for Concurrent Scavenging of H\n                    <sub>2<\/sub>\n                    S and Reactive Oxygen Species"],"prefix":"10.1002","volume":"63","author":[{"given":"Xiang","family":"Ni","sequence":"first","affiliation":[{"name":"Department of Chemistry Brown University  Providence RI 02912 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eizo","family":"Marutani","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Critical Care and Pain 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