{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T01:57:14Z","timestamp":1788573434364,"version":"build-2803163510"},"reference-count":73,"publisher":"Wiley","issue":"48","license":[{"start":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T00:00:00Z","timestamp":1730160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC3401802"],"award-info":[{"award-number":["2022YFC3401802"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22279105"],"award-info":[{"award-number":["22279105"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2024,11,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Photocatalytic utilization of methanol and nitrate as carbon and nitrogen sources for the direct synthesis of amino acids could provide a sustainable way for the valorization of green \u201cliquid sunlight\u201d and nitrate waste. In this study, we develop an efficient photochemical method to synthesize glycine directly from methanol and nitrate, which cascades the C\u2212C coupling to form glycol, nitrate reduction to NH\n                    <jats:sub>3<\/jats:sub>\n                    , and finally C\u2212N coupling to generate glycine. Interestingly, the involved photocatalytic tandem reactions show a synergistic effect, in which the presence of nitrate is the dominant factor to enable the overall reaction and reach high synthetic efficiency. Ba\n                    <jats:sup>2+<\/jats:sup>\n                    \u2212TiO\n                    <jats:sub>2<\/jats:sub>\n                    nanoparticles are confirmed as a feasible and efficient catalyst system for the photosynthesis of glycine with a remarkable glycine photosynthesis rate of 870\u2005\u03bcmol\u2009g\n                    <jats:sub>cat<\/jats:sub>\n                    <jats:sup>\u22121<\/jats:sup>\n                    \u2009h\n                    <jats:sup>\u22121<\/jats:sup>\n                    under optimal conditions. This work establishes a novel catalytic system for amino acid synthesis from methanol and nitrate under mild conditions. These results also allow us to further suppose the formation pathways of amino acids on the primitive earth, as an extension to proposals based on the Miller\u2010Urey experiments.\n                  <\/jats:p>","DOI":"10.1002\/anie.202405370","type":"journal-article","created":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T07:30:54Z","timestamp":1723534254000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Photocatalytic Synthesis of Glycine from Methanol and Nitrate"],"prefix":"10.1002","volume":"63","author":[{"given":"Peifeng","family":"Li","sequence":"first","affiliation":[{"name":"Department of Chemistry Zhejiang University  Hangzhou 310058 China"},{"name":"Center of Artificial Photosynthesis for Solar Fuels and Department of Chemistry, School of Science and Research Center for Industries of the Future Westlake University  Hangzhou 310024 China"},{"name":"Institute of Natural Sciences Westlake Institute for Advanced Study  Hangzhou 310024 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanghui","family":"Zhao","sequence":"additional","affiliation":[{"name":"Center of Artificial Photosynthesis for Solar Fuels and Department of Chemistry, School of Science and Research Center for Industries of the Future Westlake University  Hangzhou 310024 China"},{"name":"Institute of Natural Sciences Westlake Institute for Advanced Study  Hangzhou 310024 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaixuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Center of Artificial Photosynthesis for Solar Fuels and Department of Chemistry, School of Science and Research Center for Industries of the Future Westlake University  Hangzhou 310024 China"},{"name":"Institute of Natural Sciences Westlake Institute for Advanced Study  Hangzhou 310024 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Wang","sequence":"additional","affiliation":[{"name":"Center of Artificial Photosynthesis for Solar Fuels and Department of Chemistry, School of Science and Research Center for Industries of the Future Westlake University  Hangzhou 310024 China"},{"name":"Institute of Natural Sciences Westlake Institute for Advanced Study  Hangzhou 310024 China"},{"name":"Division of Solar Energy Conversion and Catalysis at Westlake University Zhejiang Baima Lake Laboratory Co., Ltd.  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