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This report presents a series of visible\u2010light\u2010driven multicomponent reactions of amines, carbon disulfide, and olefins for the mild and versatile synthesis of linear thioamides and cyclic thiolactams. The use of inexpensive and readily available carbon disulfide as the thiocarbonyl source in a radical pathway enables the facile assembly of structurally diverse amine moieties with non\u2010nucleophilic carbon\u2010based reaction partners. Radical thiocarbamoylative cyclization provides a practical protocol that complements traditional approaches to thiolactams relying on deoxythionation. Mechanistic studies reveal that direct photoexcitation of in situ formed dithiocarbamate anions as well as versatile photoinduced electron transfer with diverse electron acceptors are key to the reactions.<\/jats:p>","DOI":"10.1002\/anie.202409605","type":"journal-article","created":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T14:26:30Z","timestamp":1720448790000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Visible\u2010Light\u2010Driven Multicomponent Reactions for the Versatile Synthesis of Thioamides by Radical Thiocarbamoylation"],"prefix":"10.1002","volume":"63","author":[{"given":"Hong\u2010Mei","family":"Guo","sequence":"first","affiliation":[{"name":"Hubei Key Laboratory of Bioinorganic Chemistry &amp; Materia Medica School of Chemistry and Chemical Engineering Huazhong University of Science and Technology  Wuhan 430074 P. R. 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