{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T16:24:36Z","timestamp":1776443076071,"version":"3.51.2"},"reference-count":80,"publisher":"Wiley","issue":"50","license":[{"start":{"date-parts":[[2024,11,2]],"date-time":"2024-11-02T00:00:00Z","timestamp":1730505600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["GM118614"],"award-info":[{"award-number":["GM118614"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2024,12,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Here, we report a robust nickel\u2010catalyzed <jats:italic>\u03b1,\u03b2\u2010<\/jats:italic>dehydrogenation process designed for substrates that contain electron\u2010withdrawing sulfur and phosphorus groups. Leveraging the formation of organozinc intermediates and the utilization of a mild oxidant, allyl methyl carbonate, this methodology exhibits remarkable efficiency and outstanding diastereoselectivities across a diverse array of substrates, achieving <jats:italic>E\u2009:\u2009Z<\/jats:italic> ratios exceeding 20\u2009:\u20091. Investigation through deuterium incorporation studies and an analysis of the reaction sequence leading to the formation of the dehydrogenative allylation side product, provide useful insights into reaction optimization.<\/jats:p>","DOI":"10.1002\/anie.202411859","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T11:46:36Z","timestamp":1726141596000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<i>\u03b1<\/i>,<i>\u03b2<\/i>\u2010Dehydrogenation Adjacent to Sulfur\u2010 and Phosphorus\u2010 Containing Compounds"],"prefix":"10.1002","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6728-4923","authenticated-orcid":false,"given":"Yang","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Chemistry Yale University  225 Prospect Street New Haven Connecticut 06520-8107 United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8741-7236","authenticated-orcid":false,"given":"Timothy","family":"Newhouse","sequence":"additional","affiliation":[{"name":"Department of Chemistry Yale University  225 Prospect Street New Haven Connecticut 06520-8107 United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,2]]},"reference":[{"key":"e_1_2_3_1_1","unstructured":"For selected examples in material science see:"},{"key":"e_1_2_3_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/acssuschemeng.8b05550"},{"key":"e_1_2_3_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.1c00487"},{"key":"e_1_2_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.medidd.2020.100063"},{"key":"e_1_2_3_5_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm501105n"},{"key":"e_1_2_3_6_1","unstructured":"For selected examples and reviews see:"},{"key":"e_1_2_3_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm049171v"},{"key":"e_1_2_3_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/med.20074"},{"key":"e_1_2_3_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja106204m"},{"key":"e_1_2_3_10_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm401788m"},{"key":"e_1_2_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2022.114255"},{"key":"e_1_2_3_12_1","unstructured":"\u00a0"},{"key":"e_1_2_3_13_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm00017a002"},{"key":"e_1_2_3_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja0390294"},{"key":"e_1_2_3_15_2","doi-asserted-by":"publisher","DOI":"10.1039\/b702826a"},{"key":"e_1_2_3_16_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm701141u"},{"key":"e_1_2_3_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.5b00336"},{"key":"e_1_2_3_18_1","unstructured":"For selected examples see:"},{"key":"e_1_2_3_19_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja0619455"},{"key":"e_1_2_3_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200701367"},{"key":"e_1_2_3_21_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja072890p"},{"key":"e_1_2_3_22_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol9003349"},{"key":"e_1_2_3_23_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja306731u"},{"key":"e_1_2_3_24_2","doi-asserted-by":"publisher","DOI":"10.1021\/cs500261k"},{"key":"e_1_2_3_25_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja5079877"},{"key":"e_1_2_3_26_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8QO01291A"},{"key":"e_1_2_3_27_1","unstructured":"\u00a0"},{"key":"e_1_2_3_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-0690(200003)2000:6<879::AID-EJOC879>3.0.CO;2-E"},{"key":"e_1_2_3_29_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo7016197"},{"key":"e_1_2_3_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b02312"},{"key":"e_1_2_3_31_1","unstructured":"\u00a0"},{"key":"e_1_2_3_32_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja01159a005"},{"key":"e_1_2_3_33_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-1980-29213"},{"key":"e_1_2_3_34_2","doi-asserted-by":"publisher","DOI":"10.1039\/c39830001281"},{"key":"e_1_2_3_35_1","unstructured":"For selected examples see:"},{"key":"e_1_2_3_36_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo01256a081"},{"key":"e_1_2_3_37_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo981100e"},{"key":"e_1_2_3_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/1099-0690(200008)2000:15<2787::AID-EJOC2787>3.0.CO;2-Z"},{"key":"e_1_2_3_39_1","unstructured":"For selected examples see:"},{"key":"e_1_2_3_40_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr020109k"},{"key":"e_1_2_3_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(01)02293-6"},{"key":"e_1_2_3_42_1","unstructured":"For selected examples see:"},{"key":"e_1_2_3_43_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo00400a041"},{"key":"e_1_2_3_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)93676-1"},{"key":"e_1_2_3_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(03)00682-3"},{"key":"e_1_2_3_46_1","unstructured":"For selected examples see:"},{"key":"e_1_2_3_47_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo502328j"},{"key":"e_1_2_3_48_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol503114n"},{"key":"e_1_2_3_49_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b00461"},{"key":"e_1_2_3_50_1","unstructured":"For selected examples see:"},{"key":"e_1_2_3_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)88150-3"},{"key":"e_1_2_3_52_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.7b00994"},{"key":"e_1_2_3_53_1","unstructured":"For selected examples see:"},{"key":"e_1_2_3_54_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-1980-29060"},{"key":"e_1_2_3_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2012.01.135"},{"key":"e_1_2_3_56_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo5010845"},{"key":"e_1_2_3_57_2","doi-asserted-by":"publisher","DOI":"10.1039\/C3OB42522C"},{"key":"e_1_2_3_58_2","doi-asserted-by":"publisher","DOI":"10.1039\/C4GC00542B"},{"key":"e_1_2_3_59_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5OB00417A"},{"key":"e_1_2_3_60_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b00461"},{"key":"e_1_2_3_61_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.5b00558"},{"key":"e_1_2_3_62_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b01037"},{"key":"e_1_2_3_63_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2016.01.042"},{"key":"e_1_2_3_64_2","doi-asserted-by":"publisher","DOI":"10.1039\/C6RA17842A"},{"key":"e_1_2_3_65_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.7b00994"},{"key":"e_1_2_3_66_2","doi-asserted-by":"publisher","DOI":"10.1039\/D0CC00784F"},{"key":"e_1_2_3_67_2","doi-asserted-by":"publisher","DOI":"10.1039\/D1OB01435H"},{"key":"e_1_2_3_68_2","doi-asserted-by":"publisher","DOI":"10.1039\/D3GC02284F"},{"key":"e_1_2_3_69_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b00165"},{"key":"e_1_2_3_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-42392-2"},{"key":"e_1_2_3_71_1","unstructured":"\u00a0"},{"key":"e_1_2_3_72_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b02243"},{"key":"e_1_2_3_73_2","first-page":"331","volume":"27","author":"Turlik A.","year":"2016","journal-title":"Synlett"},{"key":"e_1_2_3_74_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b12924"},{"key":"e_1_2_3_75_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201706893"},{"key":"e_1_2_3_76_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b03818"},{"key":"e_1_2_3_77_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b12706"},{"key":"e_1_2_3_78_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.0c00787"},{"key":"e_1_2_3_79_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202200602"},{"key":"e_1_2_3_80_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202303099"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202411859","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T07:29:32Z","timestamp":1759303772000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.202411859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,2]]},"references-count":80,"journal-issue":{"issue":"50","published-print":{"date-parts":[[2024,12,9]]}},"alternative-id":["10.1002\/anie.202411859"],"URL":"https:\/\/doi.org\/10.1002\/anie.202411859","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,2]]},"assertion":[{"value":"2024-06-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202411859"}}