{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T02:21:44Z","timestamp":1791598904517,"version":"4.3.4"},"reference-count":45,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T00:00:00Z","timestamp":1730937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CHE-2107602"],"award-info":[{"award-number":["CHE-2107602"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["DGE-2022168"],"award-info":[{"award-number":["DGE-2022168"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006955","name":"Office of Extramural Research","doi-asserted-by":"publisher","award":["F31GM151758"],"award-info":[{"award-number":["F31GM151758"]}],"id":[{"id":"10.13039\/100006955","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01GM113030"],"award-info":[{"award-number":["R01GM113030"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2025,1,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Hydrogen sulfide (H\n                    <jats:sub>2<\/jats:sub>\n                    S) and nitric oxide (NO) are important gaseous biological signaling molecules that are involved in complex cellular pathways. A number of physiological processes require both H\n                    <jats:sub>2<\/jats:sub>\n                    S and NO, which has led to the proposal that different H\n                    <jats:sub>2<\/jats:sub>\n                    S\/NO\u22c5 crosstalk species, including thionitrite (SNO\n                    <jats:sup>\u2212<\/jats:sup>\n                    ) and perthionitrite (SSNO\n                    <jats:sup>\u2212<\/jats:sup>\n                    ), are responsible for this observed codependence. Despite the importance of these S\/N hybrid species, the reported properties and characterization, as well as the fundamental pathways of formation and subsequent reactivity, remain poorly understood. Herein we report new experimental insights into the fundamental reaction chemistry of pathways to form SNO\n                    <jats:sup>\u2212<\/jats:sup>\n                    and SSNO\n                    <jats:sup>\u2212<\/jats:sup>\n                    , including mechanisms for proton\u2010mediated interconversion. In addition, we demonstrate new modes of reactivity with other sulfur\u2010containing potential crosstalk species, including carbonyl sulfide (COS).\n                  <\/jats:p>","DOI":"10.1002\/anie.202413092","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T12:33:32Z","timestamp":1727786012000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Experimental Insights into the Formation, Reactivity, and Crosstalk of Thionitrite (SNO\n                    <sup>\u2212<\/sup>\n                    ) and Perthionitrite (SSNO\n                    <sup>\u2212<\/sup>\n                    )"],"prefix":"10.1002","volume":"64","author":[{"given":"Amanda G.","family":"Davis","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry Materials Science Institute Knight Campus for Accelerating Scientific Impact Institute of Molecular Biology 1253 University of Oregon  Eugene Oregon 97403 United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3604-653X","authenticated-orcid":false,"given":"Michael D.","family":"Pluth","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry Materials Science Institute Knight Campus for Accelerating Scientific Impact Institute of Molecular Biology 1253 University of Oregon  Eugene Oregon 97403 United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,7]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1996.271.5.C1424"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2019.07.001"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0211hyp"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00205"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.12077"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.116.235119"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1202916109"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X231169579"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-008-0519-0"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2023.05.010"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.02.154"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2009.00645.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.8b02592"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja3009693"},{"key":"e_1_2_8_15_1","first-page":"277","volume-title":"Advances in Inorganic Chemistry, Vol.\u200570","author":"Marcolongo J. P.","year":"2017"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.9b01978"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0104(84)85116-2"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/j100304a014"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202313187"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c00394"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b11332"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b05886"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2013.12.031"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.6b01660"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2016.09.022"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsfs.2016.0139"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.5b00831"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1515\/znb-1985-1203"},{"key":"e_1_2_8_29_1","unstructured":"E. Victor (2014) Reactions of S-nitrosothiols with biomimetic iron complexes and other transition metals. PhD Thesis. MIT."},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202104906"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202001450"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202204570"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6CP06314D"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201503353"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0SC01625J"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1021\/tx200526y"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.3c01976"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi973153g"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2017.7119"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr50016a002"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1102722"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac60095a044"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0CC04528D"},{"key":"e_1_2_8_44_1","unstructured":"An analogous experiment with CO2was performed in which gaseous CO2was sparged through a solution of [PPN][SNO] which resulting in the minor formation of SSNO\u2212. We proposed this reactivity was due to CO2acting as a Lewis acid which activated the SNO\u2212thus being subject to minor nucleophilic attack."},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b08084"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/am-pdf\/10.1002\/anie.202413092","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202413092","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T04:19:17Z","timestamp":1747282757000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.202413092"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,7]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1,2]]}},"alternative-id":["10.1002\/anie.202413092"],"URL":"https:\/\/doi.org\/10.1002\/anie.202413092","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.26434\/chemrxiv-2024-pv3xc","asserted-by":"object"}]},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,7]]},"assertion":[{"value":"2024-07-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202413092"}}