{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:00:08Z","timestamp":1777946408069,"version":"3.51.4"},"reference-count":74,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T00:00:00Z","timestamp":1731456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T00:00:00Z","timestamp":1731456000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFA1500100"],"award-info":[{"award-number":["2021YFA1500100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2025,1,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study addresses a challenge in organic synthetic chemistry: the direct cleavage of amide bonds, which is typically hampered by the thermodynamic stability of the C(Ar)\u2212C(acyl) bond. Previous methods often rely on \u201cCO\u201d extrusion\u2010jointing transition metal\u2010catalyzed process and require activated tertiary amides, limiting their applicability due to incompatibility with reactive functional groups such as halogens. Herein, we report a transition metal\u2010free approach for the deamidative cyclization of biaryl diamides via a radical process, yielding dibenzolactam derivatives. Along this line, we have developed the desulfonamidative cyclization of biaryl disulfonamides to produce dibenzosultams through direct nucleophilic aromatic substitution, demonstrating high selectivity for unsymmetrical structures. Additionally, unsymmetrical sulfamoyl biaryl amides, containing both amide and sulfonamide functionalities, can selectively undergo desulfonamidative coupling with the amide to form dibenzolactams, which offers a complementary synthetic pathway to unsymmetric dibenzolactams. These protocols exhibit excellent compatibility with reactive functional groups, including halogens, providing an innovative synthetic toolbox for the development of thermally activated delayed fluorescence (TADF) materials used in organic light emitting diodes (OLEDs). DMAC\u2010PDO, incorporating a dibenzolactam as the acceptor unit, serves as an efficient blue TADF emitter with a maximum external quantum efficiency (EQE\n                    <jats:sub>max<\/jats:sub>\n                    ) of 23.4\u2009%.\n                  <\/jats:p>","DOI":"10.1002\/anie.202416518","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T10:49:58Z","timestamp":1729507798000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["De(sulfon)amidative Cyclization: The Synthesis of Dibenzolactams and Dibenzosultams for Organic Light Emitting Diode Materials"],"prefix":"10.1002","volume":"64","author":[{"given":"Anping","family":"Luo","sequence":"first","affiliation":[{"name":"Key Laboratory of Green Chemistry and Technology of Ministry of Education College of Chemistry Sichuan University  29 Wangjiang Road Chengdu 610064 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhijie","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry and Technology of Ministry of Education College of Chemistry Sichuan University  29 Wangjiang Road Chengdu 610064 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haohua","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Antiviral Drugs Pingyuan Laboratory Henan Normal University  Xinxiang Henan 453007 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry and Technology of Ministry of Education College of Chemistry Sichuan University  29 Wangjiang Road Chengdu 610064 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyu","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry and Technology of Ministry of Education College of Chemistry Sichuan University  29 Wangjiang Road Chengdu 610064 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengyang","family":"Bin","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry and Technology of Ministry of Education College of Chemistry Sichuan University  29 Wangjiang Road Chengdu 610064 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yudong","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry and Technology of Ministry of Education College of Chemistry Sichuan University  29 Wangjiang Road Chengdu 610064 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0493-2388","authenticated-orcid":false,"given":"Jingsong","family":"You","sequence":"additional","affiliation":[{"name":"Key Laboratory of Green Chemistry and Technology of Ministry of Education College of Chemistry Sichuan University  29 Wangjiang Road Chengdu 610064 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,13]]},"reference":[{"key":"e_1_2_7_1_1","unstructured":"\u00a0"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm1013693"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201305718"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201610456"},{"key":"e_1_2_7_4_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201610456"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1039\/D0QM00084A"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1039\/D1SC01711J"},{"key":"e_1_2_7_7_1","unstructured":"\u00a0"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00225"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature14615"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202207346"},{"key":"e_1_2_7_10_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202207346"},{"key":"e_1_2_7_11_1","unstructured":"\u00a0"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201605012"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00182G"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8OB01832D"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.trechm.2020.08.001"},{"key":"e_1_2_7_16_1","unstructured":"\u00a0"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201507776"},{"key":"e_1_2_7_17_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201507776"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201603068"},{"key":"e_1_2_7_18_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201603068"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201611819"},{"key":"e_1_2_7_19_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201611819"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201612624"},{"key":"e_1_2_7_20_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201612624"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1039\/C9SC03169C"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1039\/D0SC01641A"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.2c01029"},{"key":"e_1_2_7_24_1","unstructured":"\u00a0"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c11277"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202314533"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202411464"},{"key":"e_1_2_7_27_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202411464"},{"key":"e_1_2_7_28_1","unstructured":"\u00a0"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8TA09383K"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3ee41948g"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja5051692"},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201506270"},{"key":"e_1_2_7_33_2","doi-asserted-by":"publisher","DOI":"10.1002\/aenm.201602663"},{"key":"e_1_2_7_34_1","unstructured":"\u00a0"},{"key":"e_1_2_7_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202305800"},{"key":"e_1_2_7_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201201318"},{"key":"e_1_2_7_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201202689"},{"key":"e_1_2_7_38_2","first-page":"1167","volume":"143","author":"Liu D.","year":"2021","journal-title":"J. Am. Chem. Soc."},{"key":"e_1_2_7_39_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202009201"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201807941"},{"key":"e_1_2_7_40_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201807941"},{"key":"e_1_2_7_41_1","unstructured":"\u00a0"},{"key":"e_1_2_7_42_2","doi-asserted-by":"publisher","DOI":"10.1002\/asia.201901744"},{"key":"e_1_2_7_43_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.6b02142"},{"key":"e_1_2_7_44_2","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.3c02758"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/128_028"},{"key":"e_1_2_7_46_1","unstructured":"\u00a0"},{"key":"e_1_2_7_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature11687"},{"key":"e_1_2_7_48_2","doi-asserted-by":"publisher","DOI":"10.1038\/natrevmats.2018.20"},{"key":"e_1_2_7_49_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202306880"},{"key":"e_1_2_7_50_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202301896"},{"key":"e_1_2_7_50_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202301896"},{"key":"e_1_2_7_51_1","unstructured":"\u00a0"},{"key":"e_1_2_7_52_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201605444"},{"key":"e_1_2_7_53_2","doi-asserted-by":"publisher","DOI":"10.1039\/C6CS00368K"},{"key":"e_1_2_7_54_2","doi-asserted-by":"publisher","DOI":"10.1039\/D2SC02201J"},{"key":"e_1_2_7_55_1","unstructured":"\u00a0"},{"key":"e_1_2_7_56_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c12234"},{"key":"e_1_2_7_57_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201915397"},{"key":"e_1_2_7_57_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201915397"},{"key":"e_1_2_7_58_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202012842"},{"key":"e_1_2_7_58_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202012842"},{"key":"e_1_2_7_59_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202205380"},{"key":"e_1_2_7_59_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202205380"},{"key":"e_1_2_7_60_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c14297"},{"key":"e_1_2_7_61_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c02872"},{"key":"e_1_2_7_62_1","unstructured":"Deposition numbers 2347418 (for DMAC-DPO) and 2371305 (for DMAC-BTZ) contain the supplementary crystallographic data for this manuscript. These data are provided free of charge by the joint Cambridge Crystallographic Data Centre and Fachinformationszentrum Karlsruhe Access Structures service."}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202416518","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anie.202416518","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202416518","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T16:58:06Z","timestamp":1777741086000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.202416518"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,13]]},"references-count":74,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,1,21]]}},"alternative-id":["10.1002\/anie.202416518"],"URL":"https:\/\/doi.org\/10.1002\/anie.202416518","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,13]]},"assertion":[{"value":"2024-08-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202416518"}}