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Herein we describe the electrochemical iodination in nitromethane with Bu<jats:sub>4<\/jats:sub>NI as iodine source and supporting electrolyte under Lewis acid\u2010free conditions in the presence of small amounts of chloride anions. The electrochemically generated reagent could be applied for the iodination of halogenated arenes, aromatic aldehydes, acids, esters, ketones, as well as nitroarenes to afford the products in good to excellent yields.<\/jats:p>","DOI":"10.1002\/anie.202422442","type":"journal-article","created":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T02:19:48Z","timestamp":1738117188000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The Electrochemical Iodination of Electron\u2010Deficient Arenes"],"prefix":"10.1002","volume":"64","author":[{"given":"Sara","family":"Torabi","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Chemie Carl von Ossietzky Universit\u00e4t Oldenburg  Carl-von-Ossietzky-Stra\u00dfe 9\u201311 26129 Oldenburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahdi","family":"Jamshidi","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Chemie Carl von Ossietzky Universit\u00e4t Oldenburg  Carl-von-Ossietzky-Stra\u00dfe 9\u201311 26129 Oldenburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5279-3378","authenticated-orcid":false,"given":"Gerhard","family":"Hilt","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Chemie Carl von Ossietzky Universit\u00e4t Oldenburg  Carl-von-Ossietzky-Stra\u00dfe 9\u201311 26129 Oldenburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,28]]},"reference":[{"key":"e_1_2_3_1_1","volume":"56","author":"Sen A.","year":"2024","journal-title":"Synthesis"},{"key":"e_1_2_3_2_1","unstructured":"\u00a0"},{"key":"e_1_2_3_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29194669"},{"key":"e_1_2_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202306679"},{"key":"e_1_2_3_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202313655"},{"key":"e_1_2_3_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-04540-4"},{"key":"e_1_2_3_7_1","unstructured":"\u00a0"},{"key":"e_1_2_3_8_2","doi-asserted-by":"publisher","DOI":"10.1039\/D3SC00801K"},{"key":"e_1_2_3_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.1c01530"},{"key":"e_1_2_3_10_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol100587j"},{"key":"e_1_2_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2005.09.051"},{"key":"e_1_2_3_12_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-1995-4089"},{"key":"e_1_2_3_13_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1067037"},{"key":"e_1_2_3_14_1","unstructured":"\u00a0"},{"key":"e_1_2_3_15_2","first-page":"399","volume":"25","author":"Leboeuf D.","year":"2014","journal-title":"Synlett"},{"key":"e_1_2_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2009.06.017"},{"key":"e_1_2_3_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo9007892"},{"key":"e_1_2_3_18_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo00063a052"},{"key":"e_1_2_3_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b02345"},{"key":"e_1_2_3_20_1","unstructured":"\u00a0"},{"key":"e_1_2_3_21_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.4c00501"},{"key":"e_1_2_3_22_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c06440"},{"key":"e_1_2_3_23_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.3c02259"},{"key":"e_1_2_3_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.9b00769"},{"key":"e_1_2_3_25_1","unstructured":"The iodination of pyridine and derivatives is hard to accomplish. 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