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Nevertheless, there remains a deficiency of methodologies for the catalytic synthesis of certain significant fluorine\u2010containing groups, such as , under mild conditions utilizing earth\u2010abundant metals. Herein, we report a method for the regioselective hydroarylation of <jats:italic>gem<\/jats:italic>\u2010difluoroalkenes under mild conditions with the aid of Ni\u2500H intermediate catalysis, which is capable of efficiently synthesizing compounds containing the  structural motifs and possesses good functional group tolerance.<\/jats:p>","DOI":"10.1002\/anie.202424714","type":"journal-article","created":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T08:55:21Z","timestamp":1743411321000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Regioselective Nickel\u2010Catalyzed Hydroarylation of <i>gem<\/i>\u2010Difluoroalkenes for the Synthesis of the ArCF2\u2212${\\rm{ArCF}}_{{2}^{-}}$ Moiety"],"prefix":"10.1002","volume":"64","author":[{"given":"Xiangyu","family":"Chen","sequence":"first","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry &amp; Chemical Biology (Ministry of Education), Department of Chemistry Tsinghua University  Haidian District Beijing 100084 P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaxing","family":"Wu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry &amp; Chemical Biology (Ministry of Education), Department of Chemistry Tsinghua University  Haidian District Beijing 100084 P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruitong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry &amp; Chemical Biology (Ministry of Education), Department of Chemistry Tsinghua University  Haidian District Beijing 100084 P.R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry &amp; Chemical Biology (Ministry of Education), Department of Chemistry Tsinghua University  Haidian District Beijing 100084 P.R. 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