{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T05:44:22Z","timestamp":1780638262032,"version":"3.54.1"},"reference-count":28,"publisher":"Wiley","issue":"28","license":[{"start":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T00:00:00Z","timestamp":1746748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","award":["CRG\/2021\/000306"],"award-info":[{"award-number":["CRG\/2021\/000306"]}],"id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001342","name":"Department of Science and Technology, Republic of South Africa","doi-asserted-by":"publisher","award":["SR\/FST\/CS\u2010II\/2017\/23C"],"award-info":[{"award-number":["SR\/FST\/CS\u2010II\/2017\/23C"]}],"id":[{"id":"10.13039\/501100001342","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2025,7,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Artificial ion channels have significant potential for various applications, including molecular communication, bio\u2010sensing, and constructing artificial cells. In this report, we demonstrated the development of a molecular communication system that transports ions across the lipid bilayers via the formation of supramolecular ion channels and harnesses chemical reactions to overcome the challenges of executing signal\u2010processing functions at the molecular level. The potent ionophore self\u2010assembles into nanochannels within the lipid bilayers and selectively transports Zn\n                    <jats:sup>2+<\/jats:sup>\n                    ions. The movement of Zn\n                    <jats:sup>2+<\/jats:sup>\n                    ions through these supramolecular ion channels enables the in situ generation of a water\u2010soluble catalytic system with tyrosine. This catalytic system promotes esterase\u2010like activity, generating fluorescent reporters from non\u2010fluorescent ester\u2010based compounds within the intravesicular environment. Furthermore, this process indicates the formation of a three\u2010input AND logic gate in the fluorescence mode, allowing the monitoring of the chemical\u2010to\u2010optical signal amplification process akin to biological counterparts. Developing these molecular communication systems to replicate the complexity of natural cellular processes opens up exciting opportunities for designing advanced biomimetic tools and exploring the fundamental principles underlying cellular communication.\n                  <\/jats:p>","DOI":"10.1002\/anie.202501634","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T01:24:04Z","timestamp":1745976244000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Supramolecular Ion Channels to Engineer Zn\n                    <sup>2+<\/sup>\n                    Ion Transport Mediated Chemical\u2010to\u2010Optical Signal Transduction"],"prefix":"10.1002","volume":"64","author":[{"given":"Soumya","family":"Srimayee","sequence":"first","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology Guwahati  Assam 781039 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biswa Mohan","family":"Prusty","sequence":"additional","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology Guwahati  Assam 781039 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mrinal Kanti","family":"Kar","sequence":"additional","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology Guwahati  Assam 781039 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathias","family":"Winterhalter","sequence":"additional","affiliation":[{"name":"Institute for Nanostructure and Solid\u2010State Physics University of Hamburg  Luruper Chaussee 149 22761 Hamburg Germany"},{"name":"School of Science Constructor University  Campus Ring 1 28759 Bremen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debasis","family":"Manna","sequence":"additional","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology Guwahati  Assam 781039 India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,9]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42004-021-00597-w"},{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.6b00330"},{"key":"e_1_2_7_3_1","first-page":"1","volume":"1","author":"Grebenstein L.","year":"2018","journal-title":"Proc. 5th ACM Int. 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