{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T19:13:00Z","timestamp":1790190780146,"version":"4.1.0"},"reference-count":55,"publisher":"Wiley","issue":"28","license":[{"start":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:00:00Z","timestamp":1747267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["92156013"],"award-info":[{"award-number":["92156013"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["92356306"],"award-info":[{"award-number":["92356306"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22305068"],"award-info":[{"award-number":["22305068"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2025,7,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We investigate two unusual phenomena in self\u2010assembly of anisotropic molecules from isotropic (Iso) melt: a heat\u2010capacity (\n                    <jats:italic>C<\/jats:italic>\n                    <jats:sub>p<\/jats:sub>\n                    ) maximum and spontaneous formation of the recently discovered chiral liquid (Iso*). Based on experiments on new nonchiral monomers, dimers, and polymers, we construct a statistical theory that shows why many complex meso\u2010structures form in two stages: continuous equilibrium growth of nano\u2010clusters in melt through strong interactions, causing the\n                    <jats:italic>C<\/jats:italic>\n                    <jats:sub>p<\/jats:sub>\n                    \u2010maximum, followed by establishment of positional long\u2010range order (LRO) through a weak first\u2010order transition. We also show why many achiral compounds additionally form an intermediate chiral Iso* liquid through what we find is a second\u2010order transition. We propose that the first process is equivalent to \u201csupramolecular polymerization\u201d in solutions, where the lack of intercluster interaction rules out LRO. Furthermore, we argue that separation into a broad and a sharp transition is universal in condensed matter where strong interactions by themselves cannot lead to LRO, either because the clusters are 1D or due to strong frustration. Clusters must first grow to critical size when, at\n                    <jats:italic>T<\/jats:italic>\n                    <jats:sub>c<\/jats:sub>\n                    , the combined weak interactions reach \u223ck\n                    <jats:sub>B<\/jats:sub>\n                    <jats:italic>T<\/jats:italic>\n                    <jats:sub>c<\/jats:sub>\n                    , prompting LRO formation. A situation similar to that in soft self\u2010assembly is seen in spin ordering in magnetic crystals, but only near 0\u00a0K.\n                  <\/jats:p>","DOI":"10.1002\/anie.202505548","type":"journal-article","created":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T08:30:05Z","timestamp":1746174605000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["On the Mechanism of Soft Self\u2010Assembly from Melt: The Ubiquitous Heat Capacity Hump and Spontaneous Melt Chirality"],"prefix":"10.1002","volume":"64","author":[{"given":"Yi\u2010nan","family":"Xue","sequence":"first","affiliation":[{"name":"Shaanxi International Research Center for Soft Matter State Key Laboratory for Mechanical Behaviour of Materials Xi'an Jiaotong University  Xi'an 710049 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang\u2010bing","family":"Zeng","sequence":"additional","affiliation":[{"name":"School of Chemical Materials and Biological Engineering University of Sheffield  Sheffield S1 3JD UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo\u2010wen","family":"Wu","sequence":"additional","affiliation":[{"name":"Shaanxi International Research Center for Soft Matter State Key Laboratory for Mechanical Behaviour of Materials Xi'an Jiaotong University  Xi'an 710049 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya\u2010xin","family":"Li","sequence":"additional","affiliation":[{"name":"School of Chemistry and Chemical Engineering Henan University of Technology  Zhengzhou 450001 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliana","family":"Cseh","sequence":"additional","affiliation":[{"name":"Romanian Academy Coriolan Dragulescu Institute of Chemistry  Timisoara 300223 Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu\u2010gui","family":"Yang","sequence":"additional","affiliation":[{"name":"Shaanxi International Research Center for Soft Matter State Key Laboratory for Mechanical Behaviour of Materials Xi'an Jiaotong University  Xi'an 710049 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Liu","sequence":"additional","affiliation":[{"name":"Shaanxi International Research Center for Soft Matter State Key Laboratory for Mechanical Behaviour of Materials Xi'an Jiaotong University  Xi'an 710049 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian A.","family":"Gehring","sequence":"additional","affiliation":[{"name":"School of Mathematical and Physical Sciences University of Sheffield  Sheffield S3 7RH UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Liu","sequence":"additional","affiliation":[{"name":"Shaanxi International Research Center for Soft Matter State Key Laboratory for Mechanical Behaviour of Materials Xi'an Jiaotong University  Xi'an 710049 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goran","family":"Ungar","sequence":"additional","affiliation":[{"name":"Shaanxi International Research Center for Soft Matter State Key Laboratory for Mechanical Behaviour of Materials Xi'an Jiaotong University  Xi'an 710049 China"},{"name":"School of Chemical Materials and Biological Engineering University of Sheffield  Sheffield S1 3JD UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,15]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat1949"},{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/026782998207631"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1039\/b502443a"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/026782998206047"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0SC01396J"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/ma00017a036"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1039\/b805965a"},{"key":"e_1_2_7_8_1","unstructured":"Y. N.Xue Y. X.Li Y. M.Tang S. G.Yang R. Y.Jia L.Cseh F.Liu X. B.Zeng G.Ungar Triclinic liquid crystal of counter\u2010rotating squashed double helices in a side\u2010chain polymer submitted."},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0TC00447B"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1051\/jp2:1994128"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201406907"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201712812"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat1413"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2SM01687G"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-28024-1"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c06164"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202403156"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/0267829031000121206"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.74.4859"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201704296"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201603226"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.74.4460"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/02678299508031087"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/15421400390242904"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/02678290500286830"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physb.2005.07.013"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/00150199608007872"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja00203a009"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1127884"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1129512"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9SC03103K"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja5035107"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijch.201900165"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200902415"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.481808"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.1667469"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp9048764"},{"key":"e_1_2_7_38_1","volume":"13","author":"Hackney N. W.","year":"2023","journal-title":"Phys. Rev. X"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11473-6"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9SM01840A"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1244827"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2039"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5CC06843F"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/cryst9030178"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202004353"},{"key":"e_1_2_7_46_1","unstructured":"S811 from BidePharmatech Co. Ltd is (S)\u2010Octan\u20102\u2010yl 4\u2010((4\u2010(hexyloxy)benzoyl)oxy)benzoate."},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRev.65.117"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1080\/00018739700101558"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1080\/00268948808075269"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr9601021"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1103\/RevModPhys.90.045004"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.89.215504"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1170027"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1170028"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.107.237802"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.202505548","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T15:21:05Z","timestamp":1767626465000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.202505548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,15]]},"references-count":55,"journal-issue":{"issue":"28","published-print":{"date-parts":[[2025,7,7]]}},"alternative-id":["10.1002\/anie.202505548"],"URL":"https:\/\/doi.org\/10.1002\/anie.202505548","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,15]]},"assertion":[{"value":"2025-03-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202505548"}}