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Within this domain, catalytic asymmetric synthesis employing CO\n                    <jats:sub>2<\/jats:sub>\n                    holds great synthetic importance. Although remarkable advances have been made in asymmetric C\u2500C bond formation using CO\n                    <jats:sub>2<\/jats:sub>\n                    as a C1 synthon in recent years, the development of incorporation of CO\n                    <jats:sub>2<\/jats:sub>\n                    as an oxygen source for asymmetric C\u2500O bond construction remains elusive, presumably due to the formidable challenge of simultaneously addressing enantioselectivity control and reaction efficiency. Here, we demonstrate the first copper\u2010catalyzed asymmetric C\u2500O bond cross\u2010coupling of allylamines and CO\n                    <jats:sub>2<\/jats:sub>\n                    in a radical strategy. The key innovation resides in the rational and strategic conversion of C\n                    <jats:sub>2<\/jats:sub>\n                    \u2010symmetric oxazoline ligands to their C\n                    <jats:sub>1<\/jats:sub>\n                    \u2010symmetric counterparts, which induces additional C\u2500N axial chirality after coordination with copper. The resultant enantioenriched fluoroalkylated 2\u2010oxazolidones can be further transformed into diverse functional compounds, including novel chiral amino alcohols for oxazoline ligand design and a potent bioactive insecticide analogue. Detailed mechanistic investigations elucidate a radical\u2010mediated pathway and establish the critical role of C\n                    <jats:sub>1<\/jats:sub>\n                    \u2010symmetric ligands in achieving efficient stereochemical control.\n                  <\/jats:p>","DOI":"10.1002\/anie.202510560","type":"journal-article","created":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T05:13:32Z","timestamp":1749705212000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Copper\u2010Catalyzed Radical Enantioconvergent C\u2500O Bond Formation for Asymmetric Cross\u2010Coupling of Allylamines and CO\n                    <sub>2<\/sub>"],"prefix":"10.1002","volume":"64","author":[{"given":"Xiaoyan","family":"Li","sequence":"first","affiliation":[{"name":"Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences  Fuzhou 350002 P.R. 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