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It is assumed that highly unsaturated carbon and nitrogen containing feedstock molecules, which form in a strongly reducing H\n                    <jats:sub>2<\/jats:sub>\n                    \u2010atmosphere were the reactive starting materials. The Hadean Earth was, however, surrounded by a CO\n                    <jats:sub>2<\/jats:sub>\n                    \u2010dominated atmosphere and the question of how under such inert conditions the biomolecules could have formed is unsolved. Here, we report that HNO and formaldehyde, which form robustly in a weakly reducing atmosphere by lightning and UV\u2010irradiation, react with SO\n                    <jats:sub>2<\/jats:sub>\n                    to produce oxime, amidoxime, and nitrile\u2010containing molecules, which react to give precursors to amino acids and all four canonical nucleosides. The small number of feedstock molecules required suggests that the molecules of life can robustly form on all types of rock planets with volcanic activity and a CO\n                    <jats:sub>2<\/jats:sub>\n                    \u2010dominated atmosphere.\n                  <\/jats:p>","DOI":"10.1002\/anie.202512374","type":"journal-article","created":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T08:15:41Z","timestamp":1756714541000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The Origin of the Feedstock Molecules for Life on the Hadean Earth"],"prefix":"10.1002","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2432-9841","authenticated-orcid":false,"given":"Nikolai","family":"Diukarev","sequence":"first","affiliation":[{"name":"Department of Chemistry Institute for Chemical Epigenetics, Ludwig\u2010Maximilians\u2010Universit\u00e4t M\u00fcnchen  W\u00fcrmtalstra\u00dfe 201 81375 Munich 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