{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T23:09:19Z","timestamp":1792883359940,"version":"4.5.0"},"reference-count":60,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2026,2,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Electrochemiluminescence (ECL) is a powerful analytical technique that generates light through electrochemically induced reactions, enabling ultrasensitive biosensing and imaging of submicrometric objects. Conventional ECL systems, such as those using Ru(bpy)\n                    <jats:sub>3<\/jats:sub>\n                    <jats:sup>2<\/jats:sup>\n                    \u207a and tri\u2010\n                    <jats:italic>n<\/jats:italic>\n                    \u2010propylamine (TPrA), require high applied potentials (oxidation at \u223c1.4\u00a0V versus Ag\/AgCl), leading to electrode surface modification and parasitic reactions. Herein, we present a novel autocatalytic ECL mechanism that drastically lowers the triggering potential to \u22120.2\u00a0V by exploiting the synergistic interplay between oxalate (C\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>4<\/jats:sub>\n                    <jats:sup>2\u2212<\/jats:sup>\n                    ) and peroxydisulfate (S\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>8<\/jats:sub>\n                    <jats:sup>2\u2212<\/jats:sup>\n                    ) radicals, mediated by Ru(NH\n                    <jats:sub>3<\/jats:sub>\n                    )\n                    <jats:sub>6<\/jats:sub>\n                    <jats:sup>3+<\/jats:sup>\n                    reduction. This system generates ECL without direct oxidation of the luminophore, but instead through a mild reduction process, relying on homogeneous radical reactions (SO\n                    <jats:sub>4<\/jats:sub>\n                    <jats:sup>\u2022<\/jats:sup>\n                    <jats:sup>\u2212<\/jats:sup>\n                    and CO\n                    <jats:sub>2<\/jats:sub>\n                    <jats:sup>\u2022<\/jats:sup>\n                    <jats:sup>\u2212<\/jats:sup>\n                    ) to populate the Ru(bpy)\n                    <jats:sub>3<\/jats:sub>\n                    <jats:sup>2<\/jats:sup>\n                    \u207a* excited state. Experimental investigation at different Ru(NH\n                    <jats:sub>3<\/jats:sub>\n                    )\n                    <jats:sub>6<\/jats:sub>\n                    <jats:sup>3+<\/jats:sup>\n                    \/S\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>8<\/jats:sub>\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>\u2212<\/jats:sup>\n                    \/C\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>4<\/jats:sub>\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>\u2212<\/jats:sup>\n                    concentration ratios, backed by finite element simulations, demonstrates the autocatalytic cycle's capability of exciting luminophores with a bandgap as high as 2.77\u00a0eV (blue\u2010emitting Ir(III) complex), while also showing a more stable ECL emission and achieving an emitting layer as thick as \u223c4.8 \u00b1 0.2\u00a0\u00b5m. These findings establish a low\u2010potential ECL pathway with a large emitting layer, extending the applicability of such nontoxic coreactants\u2014historically limited by their short\u2010lived radicals\u2014and potentially paving the way for new frontiers in ECL.\n                  <\/jats:p>","DOI":"10.1002\/anie.202524093","type":"journal-article","created":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T07:07:01Z","timestamp":1767164821000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Autocatalytic Electrochemiluminescence"],"prefix":"10.1002","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0555-8138","authenticated-orcid":false,"given":"Claudia Martinez","family":"Asenjo","sequence":"first","affiliation":[{"name":"Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum \u2212 University of Bologna  Bologna 40129 Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9960-7284","authenticated-orcid":false,"given":"Francesco","family":"Petrini","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9 ITODYS CNRS  Paris 75013 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2685-1748","authenticated-orcid":false,"given":"Alessandro","family":"Fracassa","sequence":"additional","affiliation":[{"name":"Department of Chemistry \u201cGiacomo Ciamician\u201d, Alma Mater Studiorum \u2212 University of Bologna  Bologna 40129 Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1861-1128","authenticated-orcid":false,"given":"Sara","family":"Kne\u017eevi\u0107","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9 CNRS Laboratoire Chimie de la Mati\u00e8re Condens\u00e9e de Paris LCMCP  4 Place Jussieu Paris 75005 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5960-2472","authenticated-orcid":false,"given":"Elisa","family":"D'Arrigo","sequence":"additional","affiliation":[{"name":"Univ. 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