{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T16:57:14Z","timestamp":1790528234831,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T00:00:00Z","timestamp":1790467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T00:00:00Z","timestamp":1790467200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2250061421"],"award-info":[{"award-number":["2250061421"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Boosting the O\n                    <jats:sub>2<\/jats:sub>\n                    photoactivation for efficient generation of reactive oxygen species is crucial to the synthesis of high\u2010value chemicals. Inducing strong dipole interaction is an effective strategy to strengthen the built\u2010in electric field (BIEF). However, it remains a great challenge to realize the precise regulation of polarisation orientation. Herein, a strategy to precisely control the polarity orientation of covalent organic frameworks (COFs) by regulating the regioisomerism of building blocks is proposed. Specifically, we integrated three regioisomeric thiophene derivatives into COF skeletons for H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    photosynthesis. Experimental and theoretical results show that the presence of adjacent S atoms in TTDA\u2010TAPT\u2010COF facilitates oriented dipole alignment, significantly enhancing the BIEF strength. Furthermore, this unique structure forms concave\u2010convex pore walls with adjacent double\u2010S atomic binding sites, inducing a switch of the O\n                    <jats:sub>2<\/jats:sub>\n                    adsorption configuration from Pauling\u2010type to Yeager\u2010type, thereby significantly enhancing H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    photosynthesis. This work reveals the decisive role of regional isomerisation in tuning polarity orientation and BIEF, and this strategy is expected to be extended to other photocatalytic reactions involving oxygen activation, such as organic oxidation and pollutant degradation.\n                  <\/jats:p>","DOI":"10.1002\/anie.2540246","type":"journal-article","created":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T16:35:11Z","timestamp":1790526911000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Inducing Orientation Polarisation via Regional Isomerisation in Covalent Organic Frameworks for Enhanced O\n                    <sub>2<\/sub>\n                    Photoactivation"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7028-0149","authenticated-orcid":false,"given":"Yang","family":"Deng","sequence":"first","affiliation":[{"name":"Department College of Chemistry and Chemical Engineering Institution Taiyuan University of Technology  Taiyuan P.R. 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China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengfei","family":"Li","sequence":"additional","affiliation":[{"name":"Department College of Chemistry and Chemical Engineering Institution Taiyuan University of Technology  Taiyuan P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhuang","family":"Fan","sequence":"additional","affiliation":[{"name":"Department College of Chemistry and Chemical Engineering Institution Taiyuan University of Technology  Taiyuan P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nianbo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department College of Chemistry and Chemical Engineering Institution Taiyuan University of Technology  Taiyuan P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4997-2148","authenticated-orcid":false,"given":"Xu","family":"Wu","sequence":"additional","affiliation":[{"name":"Department College of Chemistry and Chemical Engineering Institution Taiyuan University of Technology  Taiyuan P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202423157","article-title":"Identifying the Key Photosensitizing Factors Over Metal\u2013Organic Frameworks for Selective Control of 1 O2 and O2\n                  \u2212 Generation","volume":"64","author":"Ma X.\u2010L.","year":"2025","journal-title":"Angewandte Chemie International Edition"},{"key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"8941","DOI":"10.1038\/s41467-025-63997-9","article-title":"Squaric Acid\u2010Based Zwitterionic Covalent Organic Framework Induces Triple Synergy for Boosted Hydrogen Peroxide Photosynthesis","volume":"16","author":"Liu C.","year":"2025","journal-title":"Nature Communications"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"21328","DOI":"10.1021\/jacs.2c09482","article-title":"Piperazine\u2010Linked 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