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However, despite the rapidly advancing chemistry of\n                    <jats:italic>N<\/jats:italic>\n                    \u2010CF\n                    <jats:sub>3<\/jats:sub>\n                    and\n                    <jats:italic>N<\/jats:italic>\n                    \u2010CF\n                    <jats:sub>2<\/jats:sub>\n                    H amides, access to the corresponding\n                    <jats:italic>N<\/jats:italic>\n                    \u2010monofluoromethyl (\n                    <jats:italic>N<\/jats:italic>\n                    \u2010CH\n                    <jats:sub>2<\/jats:sub>\n                    F) amides remains significantly underdeveloped. Existing approaches are often constrained by the use of silver\u2010based fluorinating reagents, unstable intermediates, and limited compatibility with peptide substrates. In this study, we report an electrochemical strategy for the synthesis of\n                    <jats:italic>N<\/jats:italic>\n                    \u2010monofluoromethyl amides using fluoride as the fluorine source. Employing\n                    <jats:italic>N<\/jats:italic>\n                    \u2010CH\n                    <jats:sub>2<\/jats:sub>\n                    TMS amides as readily accessible precursors, the target framework is efficiently constructed through electrochemical oxidative activation. The transformation proceeds under mild conditions and exhibits broad compatibility with amino acid\u2010derived amides and peptide substrates of varying chain lengths.\n                  <\/jats:p>","DOI":"10.1002\/anie.5407928","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T11:08:40Z","timestamp":1788174520000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Electrochemical Desilylative Fluorination Enables Access to\n                    <i>N<\/i>\n                    \u2010Monofluoromethyl Amides and Peptides"],"prefix":"10.1002","volume":"65","author":[{"given":"Hong\u2010Hai","family":"Zhang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Physical Chemistry of Solid Surfaces Fujian Key Laboratory of Chemical Biology and College of Chemistry and Chemical Engineering Xiamen University  Xiamen 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