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By crosslinking two linker molecules with a short functional urea bridge pre\u2010synthetically, the combination of the resulting linker geometry and the UiO\u201066 framework confines the crosslink to the trigonal pore windows. This results in pocket\u2010like arrangements, as the urea bridges effectively \u201cwall off\u201d some of the pore windows. The structural implications are supported by modelling and electron crystallography. To demonstrate the functional versatility, we probe the selectivity of the obtained MOF toward aliphatic nitro compounds at low concentrations using vapor sorption measurements and compare it with other UiO\u201066 derivatives.<\/jats:p>","DOI":"10.1002\/anie.5435518","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T05:37:22Z","timestamp":1789105042000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Formation of Highly Selective Binding Pockets in UiO\u2010Type MOFs From Bridged Linkers"],"prefix":"10.1002","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5881-9900","authenticated-orcid":false,"given":"Tobias","family":"Hennig","sequence":"first","affiliation":[{"name":"Institute of Inorganic Chemistry Leibniz University Hannover  Hannover 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