{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T09:00:26Z","timestamp":1790067626227,"version":"4.0.1"},"reference-count":59,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22401237"],"award-info":[{"award-number":["22401237"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100032572","name":"Westlake Education Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100032572","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Integrating chirality into organic open\u2010shell architectures holds immense promise for molecular spintronics and advanced optoelectronics. However, achieving simultaneous chemical persistence, configurational stability, and practical synthetic accessibility remains a formidable challenge. Here, we report a modular strategy for persistent singlet chiral diradicals based on a C\n                    <jats:sub>2<\/jats:sub>\n                    \u2010symmetric bibenzo[\n                    <jats:italic>g<\/jats:italic>\n                    ]quinoline scaffold. Enantiopure \u03c0\u2010extended precursors were efficiently synthesized via a one\u2010pot multicomponent Povarov cyclization from commercially available BINAM, bypassing chiral HPLC resolution. Upon reduction, the monoradical intermediates exhibit a rare singly unoccupied molecular orbital SUMO\u2013LUMO inversion (SLI) electronic configuration. Strategic N\u2010protonation and steric shielding at high spin\u2010density sites dramatically enhance stability while preserving the SLI character, enabling unambiguous assignment of a singlet ground state of the reduced chiral diradicals. The resulting diradicals can serve as robust chiral redox switches, enabling highly reversible, fatigue\u2010free electrochemical cycles between the closed\u2010shell dication and neutral diradical states with full retention of the embedded chiroptical information. This work demonstrates successful implementation of the SLI pathway for persistent chiral diradicals and provides a practical platform for the rational design of configurationally stable, redox\u2010tunable open\u2010shell materials with tailored electronic and chiroptical properties.\n                  <\/jats:p>","DOI":"10.1002\/anie.6564456","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T08:09:22Z","timestamp":1790064562000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Persistent Chiral Diradicals via SUMO\u2013LUMO Inversion: Modular Synthesis, Electronic Structures, and Redox\u2010Switching Properties"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5664-2385","authenticated-orcid":false,"given":"Zekang","family":"Ma","sequence":"first","affiliation":[{"name":"School of Materials Science and Engineering Zhejiang University  Hangzhou Zhejiang 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