{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T11:13:57Z","timestamp":1788261237671,"version":"build-2803163510"},"reference-count":48,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22494633"],"award-info":[{"award-number":["22494633"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22571304"],"award-info":[{"award-number":["22571304"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22401281"],"award-info":[{"award-number":["22401281"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22494631"],"award-info":[{"award-number":["22494631"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Angew Chem Int Ed"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The century\u2010old challenge of isotope separation might be addressed by conductive metal\u2013organic framework (cMOF) thin films featuring ordered nanopores, designable charge\u2010transport pathways, and potential flexibility. However, resolving and amplifying the microscopic kinetic differences between water isotopologues within such confined spaces remains nontrivial. In this work, proton\u2010 and electron\u2010coupled two\u2010dimensional \u03c0\u2010conjugated cMOF thin films (Cu\n                    <jats:sub>1<\/jats:sub>\n                    TPB\n                    <jats:sub>0.1<\/jats:sub>\n                    \u2212\n                    <jats:italic>x<\/jats:italic>\n                    C) are fabricated through controllable layer\u2010by\u2010layer growth with oriented narrow pores and flexibility. Correlating electrical\u2010 and mass\u2010transduced gas\u2010sensor technologies, the subtle differences in the interactions of H\n                    <jats:sub>2<\/jats:sub>\n                    O and D\n                    <jats:sub>2<\/jats:sub>\n                    O with the framework were identified, revealing a complex multistage mass transport. Comparison of cMOFs with different pore sizes shows that this identification originates from distinct conduction mechanisms. Notably, the Cu\n                    <jats:sub>1<\/jats:sub>\n                    TPB\n                    <jats:sub>0.1<\/jats:sub>\n                    \u2212\n                    <jats:italic>x<\/jats:italic>\n                    C thin film with a strong space\u2010confined effect exhibits a complex multistage electrical response due to its unique proton\u2013electron\u2010coupled conduction characteristics, thereby enabling further differentiation of the transport processes of H\n                    <jats:sub>2<\/jats:sub>\n                    O and D\n                    <jats:sub>2<\/jats:sub>\n                    O on the outer surface and within the confined spaces. The oriented cMOF films therefore provide a real\u2010time platform for resolving and amplifying subtle isotope\u2010dependent transport dynamics in confined pores, offering mechanistic guidance for the design of porous materials with controlled water\u2010isotopologue transport.\n                  <\/jats:p>","DOI":"10.1002\/anie.7017206","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T10:16:36Z","timestamp":1788257796000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Space\u2010Confined Water Isotope Transport in Conductive MOF Thin Film"],"prefix":"10.1002","author":[{"given":"Sai","family":"Chu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Mesoscience and Process Engineering Institute of Process Engineering Chinese Academy of Sciences  Beijing China"},{"name":"School of Chemical Engineering University of Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahui","family":"Guo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Mesoscience and Process Engineering Institute of Process Engineering Chinese Academy of Sciences  Beijing China"},{"name":"School of Chemical Engineering University of Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiling","family":"Qi","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University  Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2301-9842","authenticated-orcid":false,"given":"Qiaozhi","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Mesoscience and Process Engineering Institute of Process Engineering Chinese Academy of Sciences  Beijing China"},{"name":"School of Chemical Engineering University of Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6040-6219","authenticated-orcid":false,"given":"Jiajia","family":"Zheng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Mesoscience and Process Engineering Institute of Process Engineering Chinese Academy of Sciences  Beijing China"},{"name":"School of Chemical Engineering University of Chinese Academy of Sciences  Beijing China"},{"name":"Laboratory of Theoretical and Computational Nanoscience National Center for Nanoscience and Technology, Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken\u2010ichi","family":"Otake","sequence":"additional","affiliation":[{"name":"Institute for Integrated Cell\u2010Material Sciences Kyoto University Institute for Advanced Study Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqi","family":"Xu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Mesoscience and Process Engineering Institute of Process Engineering Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9160-6590","authenticated-orcid":false,"given":"Rosantha","family":"Kumara","sequence":"additional","affiliation":[{"name":"Japan Synchrotron Radiation Research Institute (JASRI)  Sayo\u2010cho Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3910-9575","authenticated-orcid":false,"given":"Xi","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Luminescence and Optical Information Ministry of Education School of Physical Science and Engineering Beijing Jiaotong University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuyan","family":"Qiu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Mesoscience and Process Engineering Institute of Process Engineering Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianfei","family":"Chu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Mesoscience and Process Engineering Institute of Process Engineering Chinese Academy of Sciences  Beijing China"},{"name":"School of Chemical Engineering University of Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7480-4480","authenticated-orcid":false,"given":"Kuo","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Mesoscience and Process Engineering Institute of Process Engineering Chinese Academy of Sciences  Beijing China"},{"name":"School of Chemical Engineering University of Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6956-9543","authenticated-orcid":false,"given":"Susumu","family":"Kitagawa","sequence":"additional","affiliation":[{"name":"Institute for Integrated Cell\u2010Material Sciences Kyoto University Institute for Advanced Study Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7470-579X","authenticated-orcid":false,"given":"Zongxian","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Chemistry and Molecular Sciences Henan University  Kaifeng China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5908-266X","authenticated-orcid":false,"given":"Long","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University  Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1604-2611","authenticated-orcid":false,"given":"Ming\u2010Shui","family":"Yao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Mesoscience and Process Engineering Institute of Process Engineering Chinese Academy of Sciences  Beijing China"},{"name":"School of Chemical Engineering University of Chinese Academy of Sciences  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,1]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.73150"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1544193"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1039\/d2sc01805e"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010022\u201005310\u2010y"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11426\u2010024\u20102581\u20103"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1140\/epje\/s10189\u2010021\u201000136\u20104"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42004\u2010021\u201000544\u20109"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202104374"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2017.02.010"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasms.2006.02.008"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10450\u2010023\u201000433\u20108"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201037296\u20100"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.9b00766"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/cm301194a"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5DT01395J"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja402727d"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202206512"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnanoscienceau.3c00024"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2305125120"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c05343"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2020.213479"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10450\u2010020\u201000290\u20109"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1039\/d3ta08099d"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202114388"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aar6833"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1039\/c4ta04907a"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010018\u201005503\u2010y"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c10717"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201709558"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201908004"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.ads4369"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44160\u2010025\u201000913\u20105"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.91.215503"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41563\u2010020\u201000847\u20107"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-61845-4"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0032\u20109592(98)00112\u20105"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.1c00142"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.5c01726"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0925\u20104005(01)01043\u20107"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micromeso.2018.06.019"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2016.05.007"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201907847"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4CP03816A"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c09097"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010026\u201073221\u2010x"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202423564"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10570\u2010021\u201004189\u20108"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41928\u2010024\u201001261\u20106"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.7017206","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/anie.7017206","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.7017206","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T10:16:37Z","timestamp":1788257797000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.7017206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,1]]},"references-count":48,"alternative-id":["10.1002\/anie.7017206"],"URL":"https:\/\/doi.org\/10.1002\/anie.7017206","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,1]]},"assertion":[{"value":"2026-03-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e7017206"}}