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However, because excited\u2010state excitons involved in radiative transitions are easily quenched at elevated temperatures, achieving efficient afterglow emission under high thermal conditions remains a significant challenge. To address this issue, stimulated by the special structure of amino acid, we introduce the strong interactions, amino\u2013carboxylic acid type hydrogen\u2010bonding, into a host\u2010guest doped materials. By doping the guest molecule containing amino groups into the carboxyl\u2010rich host of butane\u20101,2,3,4\u2010tetracarboxylic acid (denoted as host D), full\u2010color afterglow emission from blue to red is realized at temperatures above 430 K. Because the four carboxyl groups of host D form a highly dense and stable hydrogen\u2010bonded network in the solid state, the doped materials maintain their high\u2010temperature afterglow performance in various non\u2010hydrogen\u2010bond\u2010donating solvents. Benefiting from the full\u2010color persistent emission and temperature\u2010dependent afterglow lifetimes, the materials further enable multidimensional information encryption and transparent liquid flow direction marker applications. The design strategy and results provide useful insights for developing high\u2010temperature phosphorescent materials and highlight their broad potential across diverse platforms.<\/jats:p>","DOI":"10.1002\/anie.7699965","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:01:36Z","timestamp":1785427296000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Amino Acid Simulated Host\u2013Guest Systems With Full\u2010Color High\u2010Temperature Organic Afterglow"],"prefix":"10.1002","volume":"65","author":[{"given":"Shuai","family":"Xia","sequence":"first","affiliation":[{"name":"School of Chemistry and Materials Engineering Wenzhou University  Wenzhou P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Xi'an Modern Chemistry Research Institute  Xi'an P. R. 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